Nanoquartz in Late Permian C1 coal and the high incidence of female lung cancer in the Pearl River Origin area: a retrospective cohort study

Tian, Linwei; Dai, Shifeng; Wang, Jianfang; Huang, Yunchao; Ho, Suzanne C.; Zhong, Yiping; Lucas, Donald; Koshland, Catherine P.

doi:10.1186/1471-2458-8-398

Cited by 67 publications

(31 citation statements)

References 15 publications

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“…Polyaromatic hydrocarbons (PAHs), nano silica particles and other substances in bituminouscoal dust and smoke are thought to be the causes of lung cancer. [6,7] In 1970, the Chinese government implemented a policy at all levels to improve coal burning stoves which could lead to improvement of indoor air quality. Despite these efforts, lung cancer incidence is still high and with an increasing trend.…”

Section: Discussionmentioning

confidence: 99%

Expression of PANDA, LincRNA-p21, PUMA in lung tissues of lung cancer patients in the Xuanwei and non-Xuanwei areas of Yunnan Province

Yang¹,

Shen²,

Y³

et al. 2017

JCMT

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Aim:To study the expression of PANDA, LincRNA-p21, and PUMA in lung tissue of patients with lung cancer from Xuanwei of Yunnan Province. Methods: Forty-five cases of lung cancer patients from Xuanwei and 42 lung cancer cases from non-Xuanwei were enrolled. Extraction of RNA was done using the Trizol kit. Real-time fluorescence quantitative PCR assay was done to obtain the relative expression. Results: Expressions of PANDA, LincRNA-p21, and PUMA in male and female patients or in squamous cell carcinoma and adenocarcinoma were not significantly different (P > 0.05). However, expression of LincRNA-p21 in Xuanwei patients was higher than non-Xuanwei patients (P < 0.05). Expression of PUMA in tumor tissue was lower than that in normal lung tissue (P < 0.05), and in Xuanwei patients was lower than non-Xuanwei patients (P < 0.05). In patients from non-Xuanwei regions, expression of LincRNA-p21 in patients with smoking index > 400 was higher than in those < 400 and non-smokers. Conclusion: Expressions of PANDA, LincRNA-p21, and PUMA in lung tissues have no gender differences or tissue specificity. High expression of LincRNA-p21 in Xuanwei patients may have relationship with cell damage caused by coal burning pollution in Xuanwei. Key words:Lung cancer, PANDA, LincRNA-p21, PUMA, Xuanwei area ABSTRACTArticle history:

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Section: Discussionmentioning

confidence: 99%

Expression of PANDA, LincRNA-p21, PUMA in lung tissues of lung cancer patients in the Xuanwei and non-Xuanwei areas of Yunnan Province

Yang¹,

Shen²,

Y³

et al. 2017

JCMT

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“…The spectra reflects low levels of quartz and kaolinite dissipated at 600˝C/2 h of thermical activation, due to their transformation into metakaolinite. Detrital quartz can also be cell-, cleat-, and fracture-fillings that are epigenetic in nature or syngenetic, such as aluminosilicates in coal [33,34,37].…”

Section: Activated Coal-mining Wastementioning

confidence: 99%

The Transformation of Coal-Mining Waste Minerals in the Pozzolanic Reactions of Cements

et al. 2016

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Abstract:The cement industry has the potential to become a major consumer of recycled waste materials that are transformed and recycled in various forms as aggregates and pozzolanic materials. These recycled waste materials would otherwise have been dumped in landfill sites, leaving hazardous elements to break down and contaminate the environment. There are several approaches for the reuse of these waste products, especially in relation to clay minerals that can induce pozzolanic reactions of special interest in the cement industry. In the present paper, scientific aspects are discussed in relation to several inert coal-mining wastes and their recycling as alternative sources of future eco-efficient pozzolans, based on activated phyllosilicates. The presence of kaolinite in this waste indicates that thermal treatment at 600˝C for 2 h transformed these minerals into a highly reactive metakaolinite over the first seven days of the pozzolanic reaction. Moreover, high contents of metakaolinite, together with silica and alumina sheet structures, assisted the appearance of layered double hydroxides through metastable phases, forming stratlingite throughout the main phase of the pozzolanic reaction after 28 days (as recommended by the European Standard) as the reaction proceeded.

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“…Tian et al (2008) and Large et al (2008) have postulated that fine-grained silica mobilized by coal combustion may be the cause for the exceptionally high incidence of lung cancer in Xuan Wei County, Yunnan Province. Exposure to mineral grains in airborne dust can also cause health problems.…”

Section: Respiratory Problemsmentioning

confidence: 99%

Medical Geology

2010

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The book series is dedicated to the United Nations International Year of Planet Earth. The aim of the Year is to raise worldwide public and political awareness of the vast (but often under-used) potential of Earth sciences for improving the quality of life and safeguarding the planet. Geoscientific knowledge can save lives and protect property if threatened by natural disasters. Such knowledge is also needed to sustainably satisfy the growing need for Earth's resources by more people. Earths scientists are ready to contribute to a safer, healthier and more prosperous society. IYPE aims to develop a new generation of such experts to find new resources and to develop land more sustainably.

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Nanoquartz in Late Permian C1 coal and the high incidence of female lung cancer in the Pearl River Origin area: a retrospective cohort study

Cited by 67 publications

References 15 publications

Expression of PANDA, LincRNA-p21, PUMA in lung tissues of lung cancer patients in the Xuanwei and non-Xuanwei areas of Yunnan Province

Expression of PANDA, LincRNA-p21, PUMA in lung tissues of lung cancer patients in the Xuanwei and non-Xuanwei areas of Yunnan Province

The Transformation of Coal-Mining Waste Minerals in the Pozzolanic Reactions of Cements

Medical Geology

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