“…To improve its therapeutic efficiency, a great deal of research has been directed towards improvements in bioavailability. The literature describes several nanocarriers which improve the intra-cellular delivery of curcumin, including solid lipid nanoparticles [ 21 , 22 , 23 , 24 ], natural [ 25 , 26 , 27 , 28 , 29 , 30 ] or synthetic [ 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 ] polymer-nanoparticles, and inorganic nanoparticles [ 39 , 40 ]. The main advantages of these nanoplatforms are their small size and large surface area, which allows the transport of the nanoparticles through the cell membrane [ 19 , 41 ].…”