Nanoporous gold for amperometric detection of amino-containing compounds

Non-enzymatic amperometric detection of phenol and catechol using nanoporous gold

“…M a n u s c r i p t 6 NPG thin films were prepared by dealloying AuSi alloy thin films as follows [31,40,41]. Au and Si were cosputter deposited on n-doped Si (1 1 0) substrates (1 cm × 2 cm) with 5 nm Ti adhesion layer and 40 nm Au layer etch stop (Fig.…”

“…1a) in a vacuum chamber working at a base pressure of 10 −6 Torr. As inherited from our previous study [31], in order to fabricate high surface area nanoporous thin films, the samples were positioned in the middle region between the Si and Au targets, as illustrated in the Fig. 1b, and under rotation mode during deposition process to achieve an Au/Si atomic ratio of about 0.45/0.55.…”

“…Especially, NPG produced from Au x Si 1-x films were reported to offer good uniformity, well-controlled porosity and thickness [30,31]. In electrochemical analysis, enhanced catalytic effect of nanoporous structures comes from its geometrical features, such as irregularity, large roughness and high porosity.…”

“…It was reported that nanoporous gold coupled with several enzymes were able to show good sensing performance in detections of ethanol (with alcohol dehydrogenase (ADH)), hydrogen peroxide (with artificial peroxidase) and glucose (with glucose oxidase) [34]. In terms of non-enzymatic sensing, NPG was found to be capable of directly detecting small molecules, such as dopamine, ascorbic acid, hydrogen peroxide, cysteine, glucose, and several environmental pollutants including p-nitrophenol, hydrazine and aniline [31,[35][36][37][38][39]. However, phenols are by far more widely used and accordingly will have much bigger environmental impact than those pollutants.…”

Effects of pore size and residual Ag on electrocatalytic properties of nanoporous gold films prepared by pulse electrochemical dealloying

“…This 3D network is very accessible for catalytic reactions. Actually, NPG materials have exhibited superior electrocatalytic activity, and can be used as ideal substrates for fabricating multifunctional electrocatalysts [4][5][6][7].…”