Nanopartikelcluster: SERS im Rampenlicht

Jin, Rongchao

doi:10.1002/ange.200906462

Cited by 5 publications

(3 citation statements)

References 42 publications

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“…[27] The molecules in the gap between the two nanospheres sense the huge electric field and give rise to dramatically greater Raman signals than that achievable with single nanoparticle. [20] Compared with the nano- www.chemeurj.org particle clusters that spontaneously formed formerly upon solvent evaporation process, [28] the arrangement of Au NPs are more ordered and the yield of gaps are higher.…”

Section: Resultsmentioning

confidence: 98%

“…SERS can provide non-destructive and ultrasensitive characterization of object molecules because it can identify molecules by their specific "fingerprints" (a series of vibrational modes that distinguish molecules with each other). [20,21] Various kinds of colloidal and solid-support-based substrates have been widely used for SERS measurements. In order to obtain good reproducibility of the SERS spectra, size-controlled nanoroughness allows the excitation of surface plasmon.…”

Section: Introductionmentioning

confidence: 99%

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Peptide Mesocrystals as Templates to Create an Au Surface with Stronger Surface‐Enhanced Raman Spectroscopic Properties

Yan

et al. 2011

Chemistry A European J

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The design and fabrication of various nanostructures with predefined geometry and composition is a big challenge of nanotechnology. Here we demonstrate an Au nanoflake film replicated from a self-assembled, well-ordered, dipeptide flower-like hierarchical architecture. Such morphology can give rise to useful and remarkable surface-enhanced Raman spectroscopy (SERS) properties. We obtained these nanostructures by using a scaffold of flake-built spherical dipeptide aggregations. Gold nanoparticles were sputtered on the surface of as-assembled dipeptide by an etching system. After removing the dipeptide templates by ethanol, a metal crust was left with a morphology similar to that of the dipeptide hierarchical structure. The different steps within the process were monitored by using electron microscopy, energy-dispersive spectrum (EDS) analysis and atomic force microscopy (AFM). Cyclic voltammetry and Raman spectra were employed to prove the SERS effect of the obtained Au substrates. The enhancement factor is estimated to be about 10(4) for 4-mercaptobenzoic acid (4-MBA) molecules on the Au nanoflake surfaces.

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Section: Resultsmentioning

confidence: 98%

Section: Introductionmentioning

confidence: 99%

Peptide Mesocrystals as Templates to Create an Au Surface with Stronger Surface‐Enhanced Raman Spectroscopic Properties

Yan

et al. 2011

Chemistry A European J

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“…As expected, the SERS signals of a dimer and a trimer show an intensity increase around 100-and 300-fold, respectively. These enhancement factors (EFs) with respect to non-interacting individual particles, are well-understood and ascribed to the generation of optical hotspots within the gaps formed between the particles 2b, 29. For tetrahedral clusters, the SERS enhancement dramatically increases up to the level of three orders of magnitude.…”

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confidence: 99%

Organized Plasmonic Clusters with High Coordination Number and Extraordinary Enhancement in Surface‐Enhanced Raman Scattering (SERS)

et al. 2012

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Metal Carbonyl–Gold Nanoparticle Conjugates for Live‐Cell SERS Imaging

Kong¹,

Lam²,

Goh³

et al. 2012

Angewandte Chemie

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The field of bioorganometallic chemistry, the junction of organometallic chemistry and biology, is coming of age. In particular, applications of metal carbonyl compounds in biological immunoassays (metallo-immunoassays), pharmaceuticals, CO therapy (CO-releasing molecules), and bioimaging have emerged. [1][2][3][4] One of the useful characteristics of metal carbonyl compounds is the strong CO stretching vibrations in the mid-IR region (1800-2200 cm À1 ); a region that is relatively free of interference from absorbance of biomolecules. This has been utilized in the development of carbonyl immunoassays, [1f] and more recently, in cell imaging, with detection techniques that include FTIR, Raman, and PTIR spectroscopy. [4] Although the first two detection methods can be carried out with readily available instrumentation, a major hindrance to IR detection for live-cell imaging is the interference from a strong absorption band of water at approximately 1600 cm À1 . Although Raman spectroscopy provides a far better spatial resolution with minimal interference from water, [5] it suffers from a low scattering cross section. [6] This necessitates a high concentration of the metal carbonyl based biotag, which poses the problem of undesired cytotoxicity and hence limits its potential in clinical applications. Furthermore, most metal carbonyl compounds have low solubility in water, thus requiring complicated bioconjugation to render them more water soluble or dispersible, and biocompatible. Therefore, there is a need to develop a highly sensitive, targeted, and low-toxicity metal carbonyl based biotag toward eventual biological applications.One promising approach to signal enhancement is surface-enhanced Raman spectroscopy (SERS); the Raman signals of molecules on colloidal gold or silver nanoparticles can be enhanced by several orders of magnitude (typically 10 6 to 10 14 ) as a result of the strong surface plasmon resonance of the nanostructured surface. This spectroscopic method has been successfully adapted to chemical sensing applications, at lower concentrations but with better detection limits, [7] and is exemplified by its use in DNA detection, [8] cancer diagnosis, [9] and detection of cellular molecules. [10] The possibility that SERS may also be used to enhance the CO stretching vibration signal of metal carbonyl compounds is attractive. Furthermore, detection by Raman microscopy will afford spatial resolution into the submicron range.The use of organometallic osmium carbonyl clusters (OM) has been demonstrated earlier; [4a] they have the advantages of being oxygen-and moisture-stable, and are very robust in comparison with other organometallic compounds. The preparation and mode of interaction of osmium carbonyl clusters with the surface of gold nanoparticles (NPs) have also been reported recently. [11] We thus envisage that the binding of an organometallic osmium carbonyl cluster, Os 3 (CO) 10 (m-H) 2 , onto the surface of gold nanoparticles (henceforth designated as "OM-NP") may significantly enhance the i...

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Nanopartikelcluster: SERS im Rampenlicht

Cited by 5 publications

References 42 publications

Peptide Mesocrystals as Templates to Create an Au Surface with Stronger Surface‐Enhanced Raman Spectroscopic Properties

Peptide Mesocrystals as Templates to Create an Au Surface with Stronger Surface‐Enhanced Raman Spectroscopic Properties

Organized Plasmonic Clusters with High Coordination Number and Extraordinary Enhancement in Surface‐Enhanced Raman Scattering (SERS)

Metal Carbonyl–Gold Nanoparticle Conjugates for Live‐Cell SERS Imaging

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