Nanoparticles for tracing acupuncture meridians and Bonghan ducts

Johng, Hyeon Min; Lee, Chang Hoon; Yoo, Jung Sun; Yoon, Tae Jong; Shin, Hak Soo; Lee, Byeong Cheol; Lee, Jin Kyu; Kim, Jung Dae; Park, Wan Su; Soh, Kwang Sup

doi:10.1007/978-3-540-36841-0_906

Cited by 2 publications

(1 citation statement)

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“…The magnetic fluorescent nanoparticles with proper surface modifications are not only nontoxic and biocompatible but also targetable to the specific area under external magnetic field [37, 38]. Johng et al observed that magnetic fluorescent nanoparticle flew along the liver meridian, where the route was same as the classical books recorded, from the acupoint Taichong (LR 3) to the acupoint Yinbao (LR 9) where a magnet was attached to the skin surface [39]. In addition, IL-PVS, a novel threadlike structure inside the lymphatic vessel, could be imaged in vivo by the magnetic fluorescent nanoparticle [40, 41].…”

Section: Seeking the Essence Of Meridiansmentioning

confidence: 99%

Traditional Acupuncture Meets Modern Nanotechnology: Opportunities and Perspectives

Zhang

Han

Litscher

2019

Evidence-Based Complementary and Alternative Medicine

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Acupuncture is an ancient method in traditional Chinese medicine (TCM). Usually acupuncture needles are inserted into the body to achieve therapeutic effects. However, there are still some challenges to achieve consensuses. What is the essence or anatomy of acupuncture meridians? How does acupuncture work? How to improve acupuncture clinical therapeutic effect? These questions may be addressed by highlighting recent developments in innovative nanotechnology. The aim of this review is to elucidate the possible applications and future potential of nanotechnology in acupuncture. Nanoparticles are promising for imaging and it may gain a better understanding of the essence of meridian. Nanotechnology enables nanochips/nanosensors providing new solutions in detection reactive molecules in vivo and in real time. The connections and changing of these molecules with needle stimulation will allow insight into the mechanisms of acupuncture. Acupuncture combined with nano-TCM could provide a great potential in some type of characteristic acupuncture therapies improvement. By virtue of nanotechnology, the acupuncture needles could be innovated as multifunction toolbox. Acupuncture needles could be considered as a method for controlled drug delivery. The nanoparticulated photothermal, magnetothermal, photodynamic agents could also be filled on the surface of needle.

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