Nanoparticles for Drug Delivery

Hasan, S. K.

doi:10.15406/jnmr.2016.03.00064

Cited by 2 publications

(2 citation statements)

References 15 publications

(11 reference statements)

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“…Nanomedicine provides a high specificity, efficacy, and sensitivity. Engineered nanomaterials can target cancer cells to controllably deliver anticancerous drugs and can help increase drug loading and improve the half-life and selective distribution by modification of their physiochemical properties [5,6].…”

Section: Traditional Vs Nanotechnological Approachmentioning

confidence: 99%

Comprehensive Review of Available Nanotechnological Techniques for Treating Nonsolid Tumors

Shekhar,

Singh,

Gupta

et al. 2023

Nano Biomedicine and Engineering

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Nanotechnology has become integral in the improvement of methodology used to identify and treat various cancers. Nanoparticles (NPs) exhibit unique features that enhance sensitivity and selectivity and subsequently reduce the time required to detect early-stage cancer through biomarkers. NPs improve the therapeutic efficiency of anticancer agents when compared with conventional methods, such as chemotherapy, and thereby eliminate toxicity and side effects, which helps improve the stability, solubility, half-life, and tumor aggregation of an anticancer drug. This also helps expedite the treatment cycle by enabling a real-time assessment, quickly circumventing various biological barriers, improving vectorization and delivery, overcoming drug resistance, and developing various paths for the manufacturing of new synthetic vaccines. Nanomedicine has usually involved studies on solid-state cancers because it can increase the cell permeability and retention effect experienced within the tumor areas to improve regional accumulation and efficacy. Nanomedicine for leukemia and lymphoma is addressed differently from solid-state cancers because of the absence of the enhanced permeability and retention effect. Nevertheless, nanomedicine has enabled the development of various modern innovative techniques for simple and noninvasive procedures for prior analysis of cancers with subsequent diffuse tumor treatment. In this assessment, we consider various unique constructs on NPs that can predominantly enhance therapeutic treatment over diffused tumors by increasing control, from preclinical testing to medicinal trials. Nanotechnology combines nanodiagnostics, nanotherapeutics, and nanotheranostics for improved imaging and diagnoses of early stage cancers. Furthermore, the primacy of nanoplatforms has been discussed for an invaluable position in this blended method. There are many types of NPs, such as organic, inorganic, and hybrid NPs. The minute size of NPs makes them ideal for intracellular uptake, and the large surface area ratio allows functional interactions with various compounds. This review also covers targeting cancerous cells via inducing lysosomal autophagy using gold NPs.

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Section: Traditional Vs Nanotechnological Approachmentioning

confidence: 99%

Comprehensive Review of Available Nanotechnological Techniques for Treating Nonsolid Tumors

Shekhar,

Singh,

Gupta

et al. 2023

Nano Biomedicine and Engineering

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“…Las nanopartículas (NPs) son partículas microscópicas cuyas dimensiones se encuentran entre los 10-100 nanómetros [nm] (Biswas y Wu, 2005;Mohanraj y Chen, 2006;Hasan, 2015). Poseen una gran diferencia en tamaño, reactividad química y absorción de energía en comparación con otros materiales a granel (Sajid y Plotka-Wasylka, 2020).…”

Section: Introductionunclassified

Nanopartículas Metálicas Por Síntesis Verde Y Su Aplicación Como Insecticidas

Zavala-Zapata,

Aguirre-Uribe,

Ramírez-Barrón

et al. 2024

Trop Subtrop Agroecosyst

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Background: The synthesis of nanoparticles from living organisms better known as biological synthesis or green synthesis has become a potential tool due to the advantages it provides compared to other existing synthesis methods. Green synthesis is presented as an environmentally friendly, safe, less toxic and cost-effective alternative. Due to these properties green nanoparticles have been implemented in the field of agriculture, mainly as nanopesticides. Objective: To review the reports on the evaluation of green nanoparticles against insects, as well as the knowledge on the possible modes of action of these nanoparticles. Methodology: A compilation of scientific information was made in different search engines, from which those that evaluated nanoparticles by green synthesis as insecticides were selected. Results: Among the modes of action caused by metallic nanoparticles, the following stand out: damage and histological changes at intestinal level, antifeedant activity, physical damage to the cuticle, decreased cell viability and inhibition of fecundity. Implications: the availability of information on nanoparticles is fundamental to be able to scientifically propose their implementation in insect pest management strategies. Conclusion: green synthesis of nanoparticles is presented as an alternative to produce nanoinsecticides; however, further research is needed on the mechanisms of action on insects, as well as their long-term repercussions on human and environmental health.

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Nanoparticles for Drug Delivery

Cited by 2 publications

References 15 publications

Comprehensive Review of Available Nanotechnological Techniques for Treating Nonsolid Tumors

Comprehensive Review of Available Nanotechnological Techniques for Treating Nonsolid Tumors

Nanopartículas Metálicas Por Síntesis Verde Y Su Aplicación Como Insecticidas

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