Nanoparticles for bioanalysis

Penn, Sharron G.; He, Lin; Natan, Michael J.

doi:10.1016/j.cbpa.2003.08.013

Cited by 499 publications

(164 citation statements)

References 62 publications

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“…70 The stable physical and chemical properties make inorganic nanoparticles suitable for use in biological assays to eliminate the shortcomings of organic fluorophores, radioactive labeling or natural enzymes, which are photobleachable, toxic, and expensive and easily degradable, respectively. 70 These multi-enzyme-like properties have been successfully used for biological detection and analysis.…”

Section: Biological Applications Bioanalysismentioning

confidence: 99%

Cerium oxide nanoparticle: a remarkably versatile rare earth nanomaterial for biological applications

2014

NPG Asia Mater

892

650

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Section: Biological Applications Bioanalysismentioning

confidence: 99%

Cerium oxide nanoparticle: a remarkably versatile rare earth nanomaterial for biological applications

2014

NPG Asia Mater

892

650

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“…The surfaces of such nanoparticles can be modified by bioactive molecules or imaging probes that can be adsorbed, coated, conjugated, or linked to them. As such, these nanoparticles were proposed for cell labeling and targeting, tissue engineering, drug delivery, drug targeting, magnetic resonance imaging etc [24]- [28]. Wide-range applications stimulated intensive study of interaction of nanoparticles with a living tissue and in particular the penetration and migration of the nanoparticles inside the tissue.…”

Section: Interaction Of Nanoparticles With Cellsmentioning

confidence: 99%

Plasmas meet nanoparticles—where synergies can advance the frontier of medicine

Kong¹,

Keidar²,

Ostrikov³

2011

J. Phys. D: Appl. Phys.

107

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To cite this version:M G Kong, M Keidar, K Ostrikov. Plasmas meet nanoparticleswhere synergies can advance the frontier of medicine. Journal of Physics D: Applied Physics, IOP Publishing, 2011, 44 (17) AbstractNanoparticles and low-temperature plasmas have been developed, independently and often along different routes, to tackle the same set of challenges in biomedicine. There are intriguing similarities and contrasts in their interactions with cells and living tissues, and these are reflected directly in the characteristics and scope of their intended therapeutic solutions, in particular their chemical reactivity, selectivity against pathogens and cancer cells, safety to healthy cells and tissues, and targeted delivery to diseased tissues. Time has come to ask the inevitable question of possible plasma-nanoparticle synergy and the related benefits to the development of effective, selective, and safe therapies for modern medicine. This perspective article offers a detailed review of the strengths and weakenesses of nanomedicine and plasma medicine as a stand-alone technology, and then provides a critical analysis of some of the major opportunities enabled by synergising the nanotechnology and the plasma technology. It is shown that the plasma-nanoparticle synergy is best captured through the plasma nanotechnology and its benefits for medicine are highly promising.

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“…It can be manipulated to obtain the desired size in the range of 0.8 to 200nm. The surface can be modified with different functional groups for gene transfection, modified into gene delivery vector by conjugation and also modified to target proteins and peptides to the cell nucleus 58,59 . Gadolinium has been studied for enhanced tumour targeted delivery by modification of the nanoparticles with folate, thiamine and poly (ethylene glycol).…”

Section: Metallic Nanoparticlesmentioning

confidence: 99%