Nanoparticle transfer biosensors for the non-invasive detection of SARS-CoV-2 antigens trapped in surgical face masks

Vaquer, Andreu; Alba-Patiño, Alejandra; Adrover-Jaume, Cristina; Russell, Steven M.; Aranda, María P.; Borges, Marcio; Mena, Joana; Castillo, Alberto del; Socías, Antònia; Martı́n, Luisa; Arellano, María Magdalena; Agudo, Miguel; González-Freire, Marta; Besalduch, Manuela; Clemente, Antonio; Barón, Enrique; Rica, Roberto de la

doi:10.1016/j.snb.2021.130347

Cited by 23 publications

(24 citation statements)

References 29 publications

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“…These biosensors are made of filter paper that has been polymer-modified, in order to hold using antibody-decorated gold nanoparticles. The polymer prevents irreversible interactions in between the paper and nanoparticles in dry circumstances, thus ensuring complete nanoparticle release when liquid is applied [ 94 ]. The World Health Organization (WHO) advises using physical and chemical variables to reduce contamination, such as masks and personal hygiene routines, as well as disinfecting surfaces, particularly those that are regularly handled, such as door handles, tables, chairs, handrails, and switches.…”

Section: Synergy Between Covid-19 Prevention Detection and Diagnosis ...mentioning

confidence: 99%

Forecasting the Post-Pandemic Effects of the SARS-CoV-2 Virus Using the Bullwhip Phenomenon Alongside Use of Nanosensors for Disease Containment and Cure

et al. 2022

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The COVID-19 pandemic has the tendency to affect various organizational paradigm alterations, which civilization hasyet to fully comprehend. Personal to professional, individual to corporate, and across most industries, the spectrum of transformations is vast. Economically, the globe has never been more intertwined, and it has never been subjected to such widespread disruption. While many people have felt and acknowledged the pandemic’s short-term repercussions, the resultant paradigm alterations will certainly have long-term consequences with an unknown range and severity. This review paper aims at acknowledging various approaches for the prevention, detection, and diagnosis of the SARS-CoV-2 virus using nanomaterials as a base material. A nanostructure is a material classification based on dimensionality, in proportion to the characteristic diameter and surface area. Nanoparticles, quantum dots, nanowires (NW), carbon nanotubes (CNT), thin films, and nanocomposites are some examples of various dimensions, each acting as a single unit, in terms of transport capacities. Top-down and bottom-up techniques are used to fabricate nanomaterials. The large surface-to-volume ratio of nanomaterials allows one to create extremely sensitive charge or field sensors (electrical sensors, chemical sensors, explosives detection, optical sensors, and gas sensing applications). Nanowires have potential applications in information and communication technologies, low-energy lightning, and medical sensors. Carbon nanotubes have the best environmental stability, electrical characteristics, and surface-to-volume ratio of any nanomaterial, making them ideal for bio-sensing applications. Traditional commercially available techniques have focused on clinical manifestations, as well as molecular and serological detection equipment that can identify the SARS-CoV-2 virus. Scientists are expressing a lot of interest in developing a portable and easy-to-use COVID-19 detection tool. Several unique methodologies and approaches are being investigated as feasible advanced systems capable of meeting the demands. This review article attempts to emphasize the pandemic’s aftereffects, utilising the notion of the bullwhip phenomenon’s short-term and long-term effects, and it specifies the use of nanomaterials and nanosensors for detection, prevention, diagnosis, and therapy in connection to the SARS-CoV-2.

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Section: Synergy Between Covid-19 Prevention Detection and Diagnosis ...mentioning

confidence: 99%

Forecasting the Post-Pandemic Effects of the SARS-CoV-2 Virus Using the Bullwhip Phenomenon Alongside Use of Nanosensors for Disease Containment and Cure

et al. 2022

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“…For example, pressing the reservoirs against surgical face masks worn by COVID‐19 patients enabled the detection of viral antigens trapped in the polypropylene layer. [ 92 ] When tested in patients with mild or no symptoms, infection by SARS‐CoV‐2 could be detected with 96.2% sensitivity and 100% specificity.…”

Section: Reservoirsmentioning

confidence: 99%

Polymer Components for Paper‐Based Analytical Devices

Campo

Vaquer

Rica

2022

Adv Materials Technologies

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In recent years, paper has become an essential substrate material for developing different types of sensors, from wearable devices to single‐use test strips and biosensors. In parallel, a polymer‐based toolbox has emerged in order to add additional functions to these paper‐based analytical devices. In this article, examples are compiled from the recent literature showing microfluidic systems based on printing impermeable polymer barriers with different methods as well as the implementation of electrochemical, fluorescent, and colorimetric polymer‐based transducers in paper‐based analytical platforms. Externally actuated or dissolvable polymer valves and reservoirs, analyte concentrators, and separation devices, as well as polymer‐based recognition elements (molecularly imprinted polymers) printed on paper substrates are also reviewed. The search has revealed a plethora of possibilities for developing complex lab‐on‐chip devices implementing different polymer‐based components in them. The ability of patterning these polymers with common printing methods that do not require specialized facilities paves the way for mass producing this kind of advanced paper‐based analytical device.

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“…In a very interesting approach, Vaquer et al [62] devised a non-invasive method for detecting SARS-CoV-2 proteins trapped in surgical face masks. The researchers used antibody-decorated gold nanostructures, which when comes in contact with SARS-CoV-2 antigens trapped in surgical face masks produce colorimetric signal; the whole assay takes only less than 10 minutes to complete.…”

Section: Role Of Nanotechnology In the Detection Of Sars-cov-2mentioning

confidence: 99%

Nanotechnology-based approaches in the fight against SARS-CoV-2

Albaz¹,

Rafeeq²,

Sain³

et al. 2021

AIMSMICRO

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<abstract> <p>The COVID-19 pandemic caused by highly-infectious virus namely severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in infection of millions of individuals and deaths across the world. The need of an hour is to find the innovative solution for diagnosis, prevention, and cure of the COVID-19 disease. Nanotechnology is emerging as one of the important tool for the same. In the present review we discuss the applications of nanotechnology-based approaches that are being implemented to speed up the development of diagnostic kits for SARS-CoV-2, development of personal protective equipments, and development of therapeutics of COVID-19 especially the vaccine development.</p> </abstract>

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Nanoparticle transfer biosensors for the non-invasive detection of SARS-CoV-2 antigens trapped in surgical face masks

Cited by 23 publications

References 29 publications

Forecasting the Post-Pandemic Effects of the SARS-CoV-2 Virus Using the Bullwhip Phenomenon Alongside Use of Nanosensors for Disease Containment and Cure

Forecasting the Post-Pandemic Effects of the SARS-CoV-2 Virus Using the Bullwhip Phenomenon Alongside Use of Nanosensors for Disease Containment and Cure

Polymer Components for Paper‐Based Analytical Devices

Nanotechnology-based approaches in the fight against SARS-CoV-2

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