Nanoparticle Size Effect on Water Vapour Adsorption by Hydroxyapatite

Szałaj, Urszula; Świderska-Środa, Anna; Chodara, Agnieszka; Gierlotka, S.; Łojkowski, Witold

doi:10.3390/nano9071005

Cited by 43 publications

(23 citation statements)

References 62 publications

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“…Polyether ether ketone (PEEK) is a candidate material for implants because of its chemical resistance and its mechanical properties matching that of the bone and radiolucency [21,27]. PEEK possesses an elastic modulus (3.2 GPa) between that of cortical (15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30) and cancellous bone (0.5-1.5 GPa) [21]. In addition, PEEK has a bio-inert and hydrophobic nature, which results in poor osseointegration characteristics [27,28].…”

Section: Introductionmentioning

confidence: 99%

Drug-Releasing Antibacterial Coating Made from Nano-Hydroxyapatite Using the Sonocoating Method

et al. 2021

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Medical implant use is associated with a risk of infection caused by bacteria on their surface. Implants with a surface that has both bone growth-promoting properties and antibacterial properties are of interest in orthopedics. In the current study, we fabricated a bioactive coating of hydroxyapatite nanoparticles on polyether ether ketone (PEEK) using the sonocoating method. The sonocoating method creates a layer by immersing the object in a suspension of nanoparticles in water and applying a high-power ultrasound. We show that the simple layer fabrication method results in a well-adhering layer with a thickness of 219 nm to 764 nm. Dropping cefuroxime sodium salt (Cef) antibiotic on the coated substrate creates a layer with a drug release effect and antibacterial activity against Staphylococcus aureus. We achieved a concentration of up to 1 mg of drug per cm2 of the coated substrate. In drug release tests, an initial burst was observed within 24 h, accompanied by a linear stable release effect. The drug-loaded implants exhibited sufficient activity against S. aureus for 24 and 168 h. Thus, the simple method we present here produces a biocompatible coating that can be soaked with antibiotics for antibacterial properties and can be used for a range of medical implants.

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Section: Introductionmentioning

confidence: 99%

Drug-Releasing Antibacterial Coating Made from Nano-Hydroxyapatite Using the Sonocoating Method

et al. 2021

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“…Specific surface area and adsorption capacity strongly increase as the particle decreases to the scale of nano-size. Chemical and physical processes that take place on their surface strongly affect the properties of particles [19]. Although hydroxyapatite nanoparticles show a great promise for medical applications; there are still concerns about the safety of using these materials in biological environments.…”

Section: Introductionmentioning

confidence: 99%

Biomimetic Synthesis of Nanocrystalline Hydroxyapatite Composites: Therapeutic Potential and Effects on Bone Regeneration

Fang

Lin

et al. 2019

IJMS

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The development of a novel alloplastic graft with both osteoinductive and osteoconductive properties is still necessary. In this study, we tried to synthesize a biomimetic hydroxyapatite microspheres (gelatin/nano-hydroxyapatite microsphere embedded with stromal cell-derived factor-1: GHM-S) from nanocrystalline hydroxyapatites and to investigate their therapeutic potential and effects on bone regeneration. In this study, hydroxyapatite was synthesized by co-precipitation of calcium hydroxide and orthophosphoric acid to gelatin solution. The microbial transglutaminase was used as the agent to crosslink the microspheres. The morphology, characterization, and thermal gravimetric analysis of microspheres were performed. SDF-1 release profile and in vitro biocompatibility and relative osteogenic gene expression were analyzed, followed by in vivo micro-computed tomography study and histological analysis. The synthesized hydroxyapatite was found to be similar to hydroxyapatite of natural bone tissue. The stromal cell-derived factor-1 was embedded into gelatin/hydroxyapatite microsphere to form the biomimetic hydroxyapatite microsphere. The stromal cell-derived factor-1 protein could be released in a controlled manner from the biomimetic hydroxyapatite microsphere and form a concentration gradient in the culture environment to attract the migration of stem cells. Gene expression and protein expression indicated that stem cells could differentiate or develop into pre-osteoblasts. The effect of bone formation by the biomimetic hydroxyapatite microsphere was assessed by an in vivo rats’ alveolar bone defects model and confirmed by micro-CT imaging and histological examination. Our findings demonstrated that the biomimetic hydroxyapatite microsphere can enhance the alveolar bone regeneration. This design has potential be applied to other bone defects.

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“…16.0%. It must be noted that microwave synthesis is also commonly and willingly employed for obtaining different nanomaterials, e.g., gold (Au) [ 406 , 407 ], silver (Ag) [ 406 , 407 , 408 ], rhodium (Rh) [ 406 , 407 ], copper (Cu) [ 406 , 407 ], hydroxyapatite (HAp) [ 409 ], zirconium dioxide (ZrO 2 ) [ 410 , 411 , 412 ], titanium dioxide (TiO 2 ) [ 413 ], silicon oxide (SiO 2 ) [ 414 ], cerium dioxide (CeO 2 ) [ 415 ], tin oxides (SnO and SnO 2 ) [ 416 ], and nanocomposites (i.a. ZrO 2 -AlO(OH) [ 417 , 418 ], MoS 2 - polydopamine-Ag [ 419 ]).…”

Section: Introductionmentioning

confidence: 99%

A Review of Microwave Synthesis of Zinc Oxide Nanomaterials: Reactants, Process Parameters and Morphologies

2020

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Zinc oxide (ZnO) is a multifunctional material due to its exceptional physicochemical properties and broad usefulness. The special properties resulting from the reduction of the material size from the macro scale to the nano scale has made the application of ZnO nanomaterials (ZnO NMs) more popular in numerous consumer products. In recent years, particular attention has been drawn to the development of various methods of ZnO NMs synthesis, which above all meet the requirements of the green chemistry approach. The application of the microwave heating technology when obtaining ZnO NMs enables the development of new methods of syntheses, which are characterised by, among others, the possibility to control the properties, repeatability, reproducibility, short synthesis duration, low price, purity, and fulfilment of the eco-friendly approach criterion. The dynamic development of materials engineering is the reason why it is necessary to obtain ZnO NMs with strictly defined properties. The present review aims to discuss the state of the art regarding the microwave synthesis of undoped and doped ZnO NMs. The first part of the review presents the properties of ZnO and new applications of ZnO NMs. Subsequently, the properties of microwave heating are discussed and compared with conventional heating and areas of application are presented. The final part of the paper presents reactants, parameters of processes, and the morphology of products, with a division of the microwave synthesis of ZnO NMs into three primary groups, namely hydrothermal, solvothermal, and hybrid methods.

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Nanoparticle Size Effect on Water Vapour Adsorption by Hydroxyapatite

Cited by 43 publications

References 62 publications

Drug-Releasing Antibacterial Coating Made from Nano-Hydroxyapatite Using the Sonocoating Method

Drug-Releasing Antibacterial Coating Made from Nano-Hydroxyapatite Using the Sonocoating Method

Biomimetic Synthesis of Nanocrystalline Hydroxyapatite Composites: Therapeutic Potential and Effects on Bone Regeneration

A Review of Microwave Synthesis of Zinc Oxide Nanomaterials: Reactants, Process Parameters and Morphologies

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