Nanoparticle Sensors for Biological Medicine

Abstract

Our work is to focus on making nanoparticles that will be used as a non-invasive method to monitor intracellular trafficking and the transfection of genes. The nanoparticles characterize gradients in oxygen tension and gene expression that occur in the biofilms. The nanoparticles are made by a few different procedures such as the Ormosil and Solgel pebble formation. The Ormosil formation makes silica particles which are used for gene delivery. This gene delivery can deliver antibiotics or any of the other medicines that could help to kill these biofilms, once something is found that can kill them these will be really useful. These nanoparticles also determine where and how much oxygen there is in the biolfilms. This can show you how bacteria are respiring and functioning and allows you to optimize conditions so you can, for example, prevent corrosion, enhance bioremediation, or enhance chemical production.

Lyophilization of Nanocapsules: Instability Sources, Formulation and Process Parameters

“…Over the last decades, nanoparticles have gained great attention in medical sciences [ 1 , 2 , 3 ] especially in the fields of imaging [ 4 , 5 , 6 , 7 , 8 , 9 , 10 ], sensing [ 11 , 12 , 13 , 14 ], gene delivery systems [ 15 , 16 , 17 , 18 , 19 , 20 , 21 ] and drug delivery [ 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 ]. Several studies have focused on the development of polymeric nanoparticles as drug delivery systems.…”