Nanoparticle Enhanced Optical Biosensing Technologies for Prostate Specific Antigen Biomarker Detection

Sarcosine Biosensor Based on Pt/g-C3N4 Nanocomposites with High Electrocatalytic Activity

“…8,10,11 Moreover, in the early stages of PCa, the tumor is not large, it is still difficult to accurately determine the tumor even if the method of "DRE combined with PSA" is adopted, thus causing deterioration of the disease. 7,12 Therefore, there is an urgent need to find more reliable and specific biomarkers to detect PCa.…”

Amperometric Sarcosine Biosensor Based on a Bi-Functional Platinum-Loaded Organic-Inorganic Hybrid Tungsten Phosphonate Material

“…6,7 PSA testing is by far the predominant screening method; Unfortunately, other diseases in the body, such as Benign Prostate Hyperplasia (BPH) and Acute Bacteria Prostatitis (ABP), can also cause elevated PSA levels in the serum, resulting in a high level of false positive test results. 8 At the same time, the PSA test has a 15% false-negative result, which causes patients to miss the best time for treatment. 9,10 In 2009, Sreekumar et al discovered that sarcosine could be used as a characteristic biomarker for PCa, [11][12][13] providing a new approach for the early detection of this disease.…”