Nanoparticle-based photodynamic therapy: new trends in wound healing applications

Cheng, Gu; Li, B.

doi:10.1016/j.mtadv.2019.100049

Cited by 27 publications

(24 citation statements)

References 96 publications

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“…Strategies such as nanoemulsions, lipid‐based nanoparticles, nanosized liposomes, polymeric nanoparticles and a series of inorganic nanostructures, such as gold, carbon nanotubes and black phosphorus nanosheets, have been investigated to enhance aPDT performance (89–91). For instance, black phosphorus nanosheets could aid in the osseointegration process because they can release phosphorus ions interacting with soluble calcium ions to accelerate mineralization and bone formation (92). Additionally, these nanosheets have been incorporated into wound dressings to treat skin tissue defects due to their biocompatibility and superior light absorption properties (93).…”

Section: Future Directions and Applicationsmentioning

confidence: 99%

Photodynamic Therapy for Biomodulation and Disinfection in Implant Dentistry: Is It Feasible and Effective?

Choe

Balhaddad

Fisher

et al. 2021

Photochem & Photobiology

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Dental implants are the most common rehabilitation and restorative treatment used to replace missing teeth. Biofilms adhere to implant surfaces to trigger implant‐associated infection and inflammatory response. Clinically, the biofilm induces a local host response with the infiltration of phagocytic immune cells. The pro‐inflammatory surroundings set off osteoclastogenesis, which leads to the septic loosening of the implant. The standard of dental care for implant‐associated infection relies on a combination of surgery and antimicrobial therapy. Antimicrobial photodynamic therapy is a noninvasive and photochemistry‐based approach capable of reducing bacterial load and modulating inflammatory responses. In this review, we explore the photobiomodulation and disinfection outcomes promoted by photodynamic therapy for implant infections, highlighting the quality of evidence on the most up‐to‐date studies, and discuss the major challenges on the advance of these therapeutic strategies.

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Section: Future Directions and Applicationsmentioning

confidence: 99%

Photodynamic Therapy for Biomodulation and Disinfection in Implant Dentistry: Is It Feasible and Effective?

Choe

Balhaddad

Fisher

et al. 2021

Photochem & Photobiology

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“…In this regard, PDT can stimulate acute inflammation, leading to alteration in the physiological processes in chronic, infected, and noninfected wounds, and improve the healing process [18]. PDT works at different stages of the healing process and accelerates overall tissue healing [19,20]. In the current study, the low-dose photodynamic therapy (LDPDT) effect on wound healing of normal and diabetic fibroblast cells was examined in vitro.…”

Section: Introductionmentioning

confidence: 97%

Low‐dose photodynamic therapy effect on closure of scratch wounds of normal and diabetic fibroblast cells: An in vitro study

Khorsandi

Fekrazad

Hamblin

2021

Journal of Biophotonics

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“…Besides its successful application as a surface modification agent, melanin has been investigated As discussed, melanin-modified materials show a prominent photothermal activity that can be exploited for several purposes. NIR light treatment has a great potential to treat infections by generating ROS, which are able to kill pathogenic microorganisms [100]. Based on this, Han et al have recently developed NIR-responsive chitosan/silk fibroin (CS/SF) cryogels incorporating PDA nanoparticles [101].…”

Section: Hydrogelsmentioning

confidence: 99%

Melanin and Melanin-Like Hybrid Materials in Regenerative Medicine

et al. 2020

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Melanins are a group of dark insoluble pigments found widespread in nature. In mammals, the brown-black eumelanins and the reddish-yellow pheomelanins are the main determinants of skin, hair, and eye pigmentation and play a significant role in photoprotection as well as in many biological functions ensuring homeostasis. Due to their broad-spectrum light absorption, radical scavenging, electric conductivity, and paramagnetic behavior, eumelanins are widely studied in the biomedical field. The continuing advancements in the development of biomimetic design strategies offer novel opportunities toward specifically engineered multifunctional biomaterials for regenerative medicine. Melanin and melanin-like coatings have been shown to increase cell attachment and proliferation on different substrates and to promote and ameliorate skin, bone, and nerve defect healing in several in vivo models. Herein, the state of the art and future perspectives of melanins as promising bioinspired platforms for natural regeneration processes are highlighted and discussed.

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Nanoparticle-based photodynamic therapy: new trends in wound healing applications

Cited by 27 publications

References 96 publications

Photodynamic Therapy for Biomodulation and Disinfection in Implant Dentistry: Is It Feasible and Effective?

Photodynamic Therapy for Biomodulation and Disinfection in Implant Dentistry: Is It Feasible and Effective?

Low‐dose photodynamic therapy effect on closure of scratch wounds of normal and diabetic fibroblast cells: An in vitro study

Melanin and Melanin-Like Hybrid Materials in Regenerative Medicine

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