Nanoparticle-Assisted Nuclear Relaxation-Based Detection of Oligonucleotides

Magnetic relaxation switching assay based on three-dimensional assembly of Fe3O4@ZIF-8 for detection of cadmium ions

“…In contrast, the magnetic relaxation switching (MRS) biosensor can be utilized in turbid and lightimpermeable media without separation and purication steps. [15][16][17] It has been widely used to analyze different targets, including heavy metals, 18 DNA, 19 viruses, 20 bacteria, 21 pesticide residues, 22,23 hormones, 24 and antibiotics. 25,26 The principles of conventional MRS biosensors generally rely on dispersion/ aggregation or altered concentration of magnetic nanoparticles (MNPs).…”