Nanoparticle and nanomineral production by fungi

Li, Qianwei; Liu, Feixue; Li, Min; Chen, Chunmao; Gadd, Geoffrey Michael

doi:10.1016/j.fbr.2021.07.003

Cited by 50 publications

(16 citation statements)

References 120 publications

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“…The use culture filtrate which is mixed with a metal salt is also common, this reduces complications in harvesting intracellular nanoparticles. The exact mechanism is often unclear, however reducing enzymes such as NADH-and NADPH-dependent reductases, nitrate and nitrite reductases, and non-enzyme and peptides with metallo-interaction activities are thought to participate in the reduction of M n+ to M 0 , thus resulting in nanoparticles [82]. Stabilization of the newly formed nanoparticles is then achieved by fungal secondary metabolites and proteins.…”

Section: Mycogenic Nanoparticlesmentioning

confidence: 99%

Fungal-derived compounds and mycogenic nanoparticles with antimycobacterial activity: a review

et al. 2022

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Tuberculosis (TB) is a persistent lung infection caused by Mycobacterium tuberculosis. The disease is characterized by high mortality rates of over 1 million per year. Unfortunately, the potency and effectiveness of currently used anti-TB drugs is gradually decreasing due to the constant development of persistence and resistance by M. tuberculosis. The adverse side effects associated with current anti-TB drugs, along with anti-TB drug resistance, present an opportunity to bio-prospect novel potent anti-TB drugs from unique sources. Fundamentally, fungi are a rich source of bioactive secondary metabolites with valuable therapeutic potential. Enhancing the potency and effectiveness of fungal-based anti-TB drug leads by chemical synthesis and/or modification with nanomaterials, may result in the discovery of novel anti-TB drugs. In this review, the antimycobacterial activity of fungal-derived compounds and mycogenic nanoparticles are summarized. Numerous fungal-derived compounds as well as some mycogenic nanoparticles that exhibit strong antimycobacterial activity that is comparable to that of approved drugs, were found. If fully explored, fungi holds the promise to become key drivers in the generation of lead compounds in TB-drug discovery initiatives.

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Section: Mycogenic Nanoparticlesmentioning

confidence: 99%

Fungal-derived compounds and mycogenic nanoparticles with antimycobacterial activity: a review

et al. 2022

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“…The ability to form nanoparticles has been found in all groups of organisms. Numerous studies have shown that plants [ 12 , 13 , 14 , 15 ], animals [ 10 , 16 , 17 ], bacteria [ 16 , 18 ], fungi [ 11 , 19 , 20 , 21 ], actinomycetes [ 22 , 23 ], algae [ 14 , 16 , 24 , 25 ], lichens [ 26 ] and viruses [ 10 ] can be successfully used to produce nanoparticles. Along with living cultures, their biomass, cell fractions, extracts, metabolites and spent media can also be used in green nanosynthesis [ 6 , 11 , 12 , 14 , 27 , 28 ], as well as various plant and animal food products [ 29 , 30 , 31 , 32 ] and organic industrial wastes [ 33 , 34 , 35 ].…”

Section: Introductionmentioning

confidence: 99%

Diversity of Biogenic Nanoparticles Obtained by the Fungi-Mediated Synthesis: A Review

2022

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Fungi are very promising biological objects for the green synthesis of nanoparticles. Biogenic synthesis of nanoparticles using different mycological cultures and substances obtained from them is a promising, easy and environmentally friendly method. By varying the synthesis conditions, the same culture can be used to produce nanoparticles with different sizes, shapes, stability in colloids and, therefore, different biological activity. Fungi are capable of producing a wide range of biologically active compounds and have a powerful enzymatic system that allows them to form nanoparticles of various chemical elements. This review attempts to summarize and provide a comparative analysis of the currently accumulated data, including, among others, our research group’s works, on the variety of the characteristics of the nanoparticles produced by various fungal species, their mycelium, fruiting bodies, extracts and purified fungal metabolites.

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“… 21 , 22 The fungal biomass provides the necessary capping agents, which are organic (usually proteinaceous) and biologically originated. 23 As a result, the nanoparticles show high biocompatibility as a general feature. Biocompatibility is one of the critical features of green-synthesized nanoparticles because of ease of binding and internalization whenever required.…”

Section: Introductionmentioning

confidence: 99%

Mycology-Nanotechnology Interface: Applications in Medicine and Cosmetology

Dhanjal¹,

Mehra²,

Bhardwaj³

et al. 2022

IJN

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In today’s time, nanotechnology is being utilized to develop efficient products in the cosmetic and pharmaceutical industries. The application of nanotechnology in transforming bioactive material into nanoscale products substantially improves their biocompatibility and enhances their effectiveness, even when used in lower quantities. There is a significant global market potential for these nanoparticles because of which research teams around the world are interested in the advancements in nanotechnology. These recent advances have shown that fungi can synthesize metallic nanoparticles via extra- and intracellular mechanisms. Moreover, the chemical and physical properties of novel metallic nanoparticles synthesised by fungi are improved by regulating the surface chemistry, size, and surface morphology of the nanoparticles. Compared to chemical synthesis, the green synthesis of nanoparticles offers a safe and sustainable approach for developing nanoparticles. Biosynthesised nanoparticles can potentially enhance the bioactivities of different cellular fractions, such as plant extracts, fungal extracts, and metabolites. The nanoparticles synthesised by fungi offer a wide range of applications. Recently, the biosynthesis of nanoparticles using fungi has become popular, and various ways are being explored to maximize nanoparticles synthesis. This manuscript reviews the characteristics and applications of the nanoparticles synthesised using the different taxa of fungi. The key focus is given to the applications of these nanoparticles in medicine and cosmetology.

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Nanoparticle and nanomineral production by fungi

Cited by 50 publications

References 120 publications

Fungal-derived compounds and mycogenic nanoparticles with antimycobacterial activity: a review

Fungal-derived compounds and mycogenic nanoparticles with antimycobacterial activity: a review

Diversity of Biogenic Nanoparticles Obtained by the Fungi-Mediated Synthesis: A Review

Mycology-Nanotechnology Interface: Applications in Medicine and Cosmetology

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