Nanomolar sensitive colorimetric assay for Mn 2+ using cysteic acid-capped silver nanoparticles and theoretical investigation of its sensing mechanism

Qi, Yanxia; Qu, Zhi‐bei; Wang, Qi-Xian; Zhang, Min; Shi, Guoyue

doi:10.1016/j.aca.2017.05.018

Cited by 12 publications

(3 citation statements)

References 31 publications

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“…Furthermore, the AgNPs modified with stabilizing agents can selectively detected Mn 2+ [27] . When these AgNPs bounded with Mn 2+ , the particles will be aggregated leading to larger particle size which causing the color change [10,28–31] . However, there were only a few reports about smartphone‐based detection of Mn 2+ .…”

Section: Introductionmentioning

confidence: 99%

“…[27] When these AgNPs bounded with Mn 2 + , the particles will be aggregated leading to larger particle size which causing the color change. [10,[28][29][30][31] However, there were only a few reports about smartphonebased detection of Mn 2 + . Nowadays, smartphone-based measurements have been applied to improve the ease and portability of detection in analytical chemistry.…”

Section: Introductionmentioning

confidence: 99%

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Functionalized Silver Nanoparticles for Rapid Detection of Mn²⁺ Employing a Smartphone Platform

et al. 2023

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This study describes the development of a simple, reliable, and low‐cost method to rapidly detect Mn2+ based on co‐functionalized silver nanoparticles (AgNPs) and the smartphone platform to be applied as an on‐site device in the field. The co‐functionalized AgNPs was investigated with other cations (Al3+, Ba2+, Ca2+, Cd2+, Co2+, Cr3+, Cu2+, Fe2+, Fe3+, K+, Li+, Mg2+, Na+, Ni2+, Pb2+ and Zn2+) at pH 3–10. The results showed that this functionalized AgNPs was selectively binded to Mn2+ at pH 10, which caused the color of the solution changing from yellow to orange‐red and can be measured by the smartphone application called PhotoMetrix. This application was used to measure color intensities based on RGB (red, green, blue) values and converted into Mn2+ concentration by using multivariate calibration curves within 10 minutes. The smartphone detection showed a high selectivity of AgNPs with Mn2+ and provided a positive coefficient correlation between the intensity of channel R and the concentration of Mn2+ with a linear range of 4.0×10−5–2.0×10−4 M (R2=0.9814) and a limit of detection of 2.7×10−5 M. Furthermore, the quantification of Mn2+ in real water samples can be successfully applied by this method. The obtained results were in close agreement with those obtained with inductively coupled plasma optical emission spectroscopy (ICP‐OES). Therefore, the development of a colorimetric system based on a smartphone system device was found to be feasible and reliable for on‐site Mn2+ detection in the real water samples.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Functionalized Silver Nanoparticles for Rapid Detection of Mn²⁺ Employing a Smartphone Platform

et al. 2023

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“…We designed the sensor through modulating coffee-ring effects by surface engineering of AuNPs, where stronger AuNP-AuNP interactions lead to the suppression of coffee-ring strains. Owing to their unique surface plasmon resonance (SPR) properties, AuNPs display size-and distance-dependent optical absorption [12] so that colorimetric assays are the most common use of AuNPs because of their high sensitivity, ease of construction, and suitability for naked-eye detection [13]. However, the applications of SPR-based AuNP colorimetric assays is often limited.…”

Section: Introductionmentioning

confidence: 99%

Biomimetic Surface Engineering to Modulate the Coffee-Ring Effect for Amyloid-β Detection in Rat Brains

Wang,

Li,

et al. 2023

Biomimetics

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Surface engineering of nanoparticles has been widely used in biosensing and assays, where sensitivity was mainly limited by plasmonic colour change or electrochemical responses. Here, we report a novel biomimetic sensing strategy involving protein-modified gold nanoparticles (AuNPs), where the modulation strategy was inspired by gastropods in inhibition of coffee-ring effects in their trail-followings. The so-called coffee-ring effect presents the molecular behaviour of AuNPs to a macroscopic ring through aggregation, and thus greatly improves sensitivity. The assay relies upon the different assembly patterns of AuNPs against analytes, resulting in the formation or suppression of coffee-ring effects by the different surface engineering of AuNPs by proteins and peptides. The mechanism of the coffee-ring formation process is examined through experimental characterizations and computational simulations. A practical coffee-ring effect assay is developed for a proof-of-concept target, amyloid β (1–42), which is a typical biomarker of Alzheimer’s disease. A novel quasi-titrimetric protocol is constructed for quantitative determination of the target molecule. The assay shows excellent selectivity and sensitivity for the amyloid β monomer, with a low detection limit of 20 pM. Combined with a fluorescent staining technique, the assay is designed as a smart sensor for amyloid β detection and fibrillation evaluation in rat cerebrospinal fluids, which is a potential point-of-care test for Alzheimer’s disease. Connections between amyloid fibrillation and different courses of brain ischaemia are also studied, with improved sensitivity, lower sample volumes that are required, convenience for rapid detection, and point-of-care testing.

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A rapid pretreatment of PVC products for high-throughput and visual detection of trace heavy metals

Yang

et al. 2019

Monatsh Chem

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Nanomolar sensitive colorimetric assay for Mn 2+ using cysteic acid-capped silver nanoparticles and theoretical investigation of its sensing mechanism

Cited by 12 publications

References 31 publications

Functionalized Silver Nanoparticles for Rapid Detection of Mn²⁺ Employing a Smartphone Platform

Functionalized Silver Nanoparticles for Rapid Detection of Mn²⁺ Employing a Smartphone Platform

Biomimetic Surface Engineering to Modulate the Coffee-Ring Effect for Amyloid-β Detection in Rat Brains

A rapid pretreatment of PVC products for high-throughput and visual detection of trace heavy metals

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Nanomolar sensitive colorimetric assay for Mn 2+ using cysteic acid-capped silver nanoparticles and theoretical investigation of its sensing mechanism

Cited by 12 publications

References 31 publications

Functionalized Silver Nanoparticles for Rapid Detection of Mn2+ Employing a Smartphone Platform

Functionalized Silver Nanoparticles for Rapid Detection of Mn2+ Employing a Smartphone Platform

Biomimetic Surface Engineering to Modulate the Coffee-Ring Effect for Amyloid-β Detection in Rat Brains

A rapid pretreatment of PVC products for high-throughput and visual detection of trace heavy metals

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Product

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Functionalized Silver Nanoparticles for Rapid Detection of Mn²⁺ Employing a Smartphone Platform

Functionalized Silver Nanoparticles for Rapid Detection of Mn²⁺ Employing a Smartphone Platform