Nanomedicine strategies to improve therapeutic agents for the prevention and treatment of preterm birth and future directions

Taylor, Jessica; Sharp, Andrew; Rannard, Steve; Arrowsmith, Sarah; McDonald, Tom O.

doi:10.1039/d2na00834c

Cited by 6 publications

(3 citation statements)

References 155 publications

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“…Nanotechnologies have the potential to be engineered for targeted delivery of therapeutic medicines specifically to the tumor site, hence enhancing their concentration and efficacy in combating cancer cells. 186 The active targeting mechanism of cancer stem cells involves the use of specific molecules or antibodies that can recognize and bind to unique markers on the surface of these cells. In which, the generic nanoparticles are modified with these targeting molecules or antibodies to specifically deliver therapeutic agents to cancer stem cells.…”

Section: Nanotechnology Advances For Gestational Trophoblastic Disord...mentioning

confidence: 99%

“…The process entails the use of nanoparticles, micelles, liposomes, and quantum dots for the precise targeting of cancer cells in the ovarian region. Nanotechnologies have the potential to be engineered for targeted delivery of therapeutic medicines specifically to the tumor site, hence enhancing their concentration and efficacy in combating cancer cells . The active targeting mechanism of cancer stem cells involves the use of specific molecules or antibodies that can recognize and bind to unique markers on the surface of these cells.…”

Section: Applications Of Nanotechnology-mediated Drug Delivery System...mentioning

confidence: 99%

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Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

Acharya,

Behera,

Behera

et al. 2024

ACS Appl. Bio Mater.

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Over the past decade, nanotechnology has seen extensive integration into biomedical applications, playing a crucial role in biodetection, drug delivery, and diagnostic imaging. This is especially important in reproductive health care, which has become an emerging and significant area of research. Global concerns have intensified around disorders such as infertility, endometriosis, ectopic pregnancy, erectile dysfunction, benign prostate hyperplasia, sexually transmitted infections, and reproductive cancers. Nanotechnology presents promising solutions to address these concerns by introducing innovative tools and techniques, facilitating early detection, targeted drug delivery, and improved imaging capabilities. Through the utilization of nanoscale materials and devices, researchers can craft treatments that are not only more precise but also more effective, significantly enhancing outcomes in reproductive healthcare. Looking forward, the future of nanotechnology in reproductive medicine holds immense potential for reshaping diagnostics, personalized therapies, and fertility preservation. The utilization of nanotechnology-driven drug delivery systems is anticipated to elevate treatment effectiveness, minimize side effects, and offer patients therapies that are not only more precise but also more efficient. This review aims to delve into the various types, properties, and preparation techniques of nanocarriers specifically designed for drug delivery in the context of reproductive disorders, shedding light on the current landscape and potential future directions in this dynamic field.

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Section: Nanotechnology Advances For Gestational Trophoblastic Disord...mentioning

confidence: 99%

Section: Applications Of Nanotechnology-mediated Drug Delivery System...mentioning

confidence: 99%

Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

Acharya,

Behera,

Behera

et al. 2024

ACS Appl. Bio Mater.

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show abstract

“…[173][174][175] However, challenges remain in optimizing delivery module efficiency and drug properties, such as biocompatibility and biodegradability. 176 Numerous ongoing clinical trials are expected to propel the advancement of novel nanotherapeutics and highlight future directions for improvement in this field. 174,175 This article selects typical examples from this area for analysis, as illustrated in Table 2.…”

Section: Latest Research Developments and Case Studiesmentioning

confidence: 99%

Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs

Liu,

Liang,

Yuhong

et al. 2024

DDDT

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This manuscript offers a comprehensive overview of nanotechnology’s impact on the solubility and bioavailability of poorly soluble drugs, with a focus on BCS Class II and IV drugs. We explore various nanoscale drug delivery systems (NDDSs), including lipid-based, polymer-based, nanoemulsions, nanogels, and inorganic carriers. These systems offer improved drug efficacy, targeting, and reduced side effects. Emphasizing the crucial role of nanoparticle size and surface modifications, the review discusses the advancements in NDDSs for enhanced therapeutic outcomes. Challenges such as production cost and safety are acknowledged, yet the potential of NDDSs in transforming drug delivery methods is highlighted. This contribution underscores the importance of nanotechnology in pharmaceutical engineering, suggesting it as a significant advancement for medical applications and patient care.

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Preeclampsia: A comprehensive review

Ali,

Ahmed,

Memon

et al. 2024

Clinica Chimica Acta

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Nanomedicine strategies to improve therapeutic agents for the prevention and treatment of preterm birth and future directions

Abstract: The World Health Organisation (WHO) estimates 15 million babies worldwide are born preterm each year, with 1 million infant mortalities and significant long-term morbidity in survivors. Whilst the past 40...

Cited by 6 publications

References 155 publications

Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

Recent Advances in Nanotechnology-Based Drug Delivery Systems for the Diagnosis and Treatment of Reproductive Disorders

Advances in Nanotechnology for Enhancing the Solubility and Bioavailability of Poorly Soluble Drugs

Preeclampsia: A comprehensive review

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