Nanomaterials: Synthesis and Applications in Theranostics

Paramasivam, Gokul; Palem, Vishnu Vardhan; Thanigaivel, S.; Vickram, Sundaram; Kishore, Somasundaram Chandra; Bellucci, Stefano

doi:10.3390/nano11123228

Cited by 41 publications

(15 citation statements)

References 137 publications

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“…Furthermore, these compounds not only facilitate the biological reduction of ions to nanoscale sizes, but also facilitate the capping of nanoparticles, which are necessary for the stability and biocompatibility of nanoparticles [ 31 , 32 , 33 ]. The top-down approach can be implemented in several ways such as laser ablation, chemical etching, sputtering, mechanical milling, and so on [ 34 ]. In addition to biological techniques, non-biological techniques are also included in the bottom-up strategy, such as spinning, laser pyrolysis, flame spraying, and atomic condensation have been mentioned.…”

Section: Traditional Methods Of Producing Npsmentioning

confidence: 99%

Recent Advances in Plant-Mediated Zinc Oxide Nanoparticles with Their Significant Biomedical Properties

et al. 2022

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Compared to traditional physical and chemical approaches, nanobiotechnology and plant-based green synthesis procedures offer significant advantages, as well as having a greater range of medical and biotechnological applications. Nanoparticles of zinc oxide (ZnO NPs) have recently been recognized as a promising option for many industries, including optics, electrics, packaged foods, and medicine, due to their biocompatibility, low cytotoxicity, and cost-effectiveness. Several studies have shown that zinc ions are important in triggering cell apoptosis by promoting the generation of reactive oxygen species (ROSs) and releasing zinc ions (Zn2+), which are toxic to cells. The toxic nature of the chemicals used in the synthesis of ZnO nanoparticles limits their clinical utility. An overview of recent developments in green ZnO NP synthesis is presented in this review, emphasizing plant parts as reducing agents and their medical applications, including their antimicrobial, anticancer, antioxidant, and anti-inflammatory properties, as well as key mechanisms of action for these applications to facilitate further research on the biomedical fields in the future.

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Section: Traditional Methods Of Producing Npsmentioning

confidence: 99%

Recent Advances in Plant-Mediated Zinc Oxide Nanoparticles with Their Significant Biomedical Properties

et al. 2022

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“…Physically breaking down a large complex into smaller parts is a critical component of the top-down strategy. Physical and mechanical procedures such as UV irradiation, lithography, laser ablation, ultrasonic sounds, and photochemical reduction create a strong energy/force to compress the macromolecule into nanoparticles [ 95 ]. The physical reduction procedures generally have quick processing durations, yielding AgNPs with a restricted size distribution range.…”

Section: Silver Nanoparticles and Their Synthesismentioning

confidence: 99%

Recent Advances in Silver Nanoparticles Containing Nanofibers for Chronic Wound Management

et al. 2022

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Infections are the primary cause of death from burns and diabetic wounds. The clinical difficulty of treating wound infections with conventional antibiotics has progressively increased and reached a critical level, necessitating a paradigm change for enhanced chronic wound care. The most prevalent bacterium linked with these infections is Staphylococcus aureus, and the advent of community-associated methicillin-resistant Staphylococcus aureus has posed a substantial therapeutic challenge. Most existing wound dressings are ineffective and suffer from constraints such as insufficient antibacterial activity, toxicity, failure to supply enough moisture to the wound, and poor mechanical performance. Using ineffective wound dressings might prolong the healing process of a wound. To meet this requirement, nanoscale scaffolds with their desirable qualities, which include the potential to distribute bioactive agents, a large surface area, enhanced mechanical capabilities, the ability to imitate the extracellular matrix (ECM), and high porosity, have attracted considerable interest. The incorporation of nanoparticles into nanofiber scaffolds constitutes a novel approach to “nanoparticle dressing” that has acquired significant popularity for wound healing. Due to their remarkable antibacterial capabilities, silver nanoparticles are attractive materials for wound healing. This review focuses on the therapeutic applications of nanofiber wound dressings containing Ag-NPs and their potential to revolutionize wound healing.

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“…The structure of free-standing 3D nanomaterials could be based on the forms of rods, cubes, spheres, porous spheres, foams, hierarchical dendrites, cross-linked nanorods, etc. Nano-cubes, fullerenes, dendrimers, and nanocages are some popular examples of 3D nanomaterials [ 37 ]. The dimensions of 3D nanomaterials can be beyond nanoscale, but they are not really the same with bulk materials.…”

Section: Classification Of Low-dimensional Nanomaterialsmentioning

confidence: 99%

A Review on Low-Dimensional Nanomaterials: Nanofabrication, Characterization and Applications

et al. 2022

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The development of modern cutting-edge technology relies heavily on the huge success and advancement of nanotechnology, in which nanomaterials and nanostructures provide the indispensable material cornerstone. Owing to their nanoscale dimensions with possible quantum limit, nanomaterials and nanostructures possess a high surface-to-volume ratio, rich surface/interface effects, and distinct physical and chemical properties compared with their bulk counterparts, leading to the remarkably expanded horizons of their applications. Depending on their degree of spatial quantization, low-dimensional nanomaterials are generally categorized into nanoparticles (0D); nanorods, nanowires, and nanobelts (1D); and atomically thin layered materials (2D). This review article provides a comprehensive guide to low-dimensional nanomaterials and nanostructures. It begins with the classification of nanomaterials, followed by an inclusive account of nanofabrication and characterization. Both top-down and bottom-up fabrication approaches are discussed in detail. Next, various significant applications of low-dimensional nanomaterials are discussed, such as photonics, sensors, catalysis, energy storage, diverse coatings, and various bioapplications. This article would serve as a quick and facile guide for scientists and engineers working in the field of nanotechnology and nanomaterials.

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Nanomaterials: Synthesis and Applications in Theranostics

Cited by 41 publications

References 137 publications

Recent Advances in Plant-Mediated Zinc Oxide Nanoparticles with Their Significant Biomedical Properties

Recent Advances in Plant-Mediated Zinc Oxide Nanoparticles with Their Significant Biomedical Properties

Recent Advances in Silver Nanoparticles Containing Nanofibers for Chronic Wound Management

A Review on Low-Dimensional Nanomaterials: Nanofabrication, Characterization and Applications

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