Nanomaterials from bacterial cellulose for antimicrobial wound dressing

Liyaskina, Elena V.; Ревин, В. В.; Paramonova, E; Назаркина, М. Г.; Pestov, Nikolay A.; Revina, Nadezhda V.; Kolesnikova, S G

doi:10.1088/1742-6596/784/1/012034

Cited by 53 publications

(36 citation statements)

References 26 publications

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“…Recently, saturation of BC with fusidic acid, a steroid antibiotic usually used for topic applications through a cream or eyedrops, was performed by simple immersion of the BC films for 1–24 h, but the release rate was not monitored. The resulting membrane was shown to be active against S. aureus (Liyaskina et al ., ). The BC/antibiotic composite membranes presented excellent biocompatibility and effective antibacterial activity against gram‐negative and gram‐positive species.…”

Section: Bacterial Cellulose Compositesmentioning

confidence: 97%

Bacterial cellulose: a versatile biopolymer for wound dressing applications

Portela

Leal

Almeida

et al. 2019

Microbial Biotechnology

412

271

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Summary Although several therapeutic approaches are available for wound and burn treatment and much progress has been made in this area, room for improvement still exists, driven by the urgent need of better strategies to accelerate wound healing and recovery, mostly for cases of severe burned patients. Bacterial cellulose (BC) is a biopolymer produced by bacteria with several advantages over vegetal cellulose, such as purity, high porosity, permeability to liquid and gases, elevated water uptake capacity and mechanical robustness. Besides its biocompatibility, BC can be modified in order to acquire antibacterial response and possible local drug delivery features. Due to its intrinsic versatility, BC is the perfect example of a biotechnological response to a clinical problem. In this review, we assess the BC main features and emphasis is given to a specific biomedical application: wound dressings. The production process and the physical–chemical properties that entitle this material to be used as wound dressing namely for burn healing are highlighted. An overview of the most common BC composites and their enhanced properties, in particular physical and biological, is provided, including the different production processes. A particular focus is given to the biochemistry and genetic manipulation of BC. A summary of the current marketed BC‐based wound dressing products is presented, and finally, future perspectives for the usage of BC as wound dressing are foreseen.

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Section: Bacterial Cellulose Compositesmentioning

confidence: 97%

Bacterial cellulose: a versatile biopolymer for wound dressing applications

Portela

Leal

Almeida

et al. 2019

Microbial Biotechnology

412

271

View full text Add to dashboard Cite

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“…The process of bio-hybridization resulted in nesting of silver nanobactericides onto bacterial cellulose forming a layer which might result in the change of mechanical properties. The bio-hybridization results in immobilization of nanobactericides thus offering advantage wherein nanobactericides are freely available onto the surface of bacterial cellulose thus increasing the rigidity and prevents from oxidation by providing chemical stability and it can offer better bactericidal properties (Liyaskina et al, 2017). The advantage of bio-hybridization in conferring the desired activity is well demonstrated in various studies.…”

Section: Resultsmentioning

confidence: 99%

“…As similar to present investigation Kirby Bauer method was followed to evaluate the bactericidal activity which can be best suited for developing functional antimicrobial agents. The use of bacterial cellulose as ideal tool to develop bio-hybrid nano composite bearing antimicrobial properties is gaining tremendous importance in recent years (Liyaskina et al, 2017). The mode of external immobilization of silver nanobactericides onto bacterial cellulose can offer better results for instance desired size tunable nanomaterials can be synthesized and loaded onto the cellulose membrane.…”

Section: Resultsmentioning

confidence: 99%

Bio-hybridization of nanobactericides with cellulose films for effective treatment against members of ESKAPE multi-drug-resistant pathogens

et al. 2018

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“…Bacterial cellulose-alginate nanocomposites were successfully produced by nanotechnology and they showed excellent antibacterial activity [81,82]. Th e synthesis of BC/chitosan or chitosan/gelatine composites with high mechanical reliability and antibacterial activity was investigated by diff erent research groups [83][84][85][86][87]. Similarly, chitosan blended with metallic nanoparticles has an eff ect on the microbial activity and wound healing [98].…”

Section: Electrospinnable Polymer Materials For Wound Dressing Applicmentioning

confidence: 99%

Review of Possible Applications of Nanofibrous Mats for Wound Dressings

Mamun¹

2019

TEK

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Skin is an important part of the human body. Its function is to control the body's homeostasis mechanism. If a skin injury occurs, it is of utmost importance to heal the skin as soon as possible. The currently available medical treatment system, however, has limited eff ectiveness on the regeneration of the structure and function of the injured skin, potentially causing wound infections and dehydration. The corresponding impact on the healing process may in the worst case also be fatal. To overcome these problems in wound dressing materials, nanofi brous mats are excellent candidates for wound treatment and management. Such wound dressings can be found in biomedical applications not only in drug delivery, but also as antibacterial and antimicrobial materials, and as materials for the regeneration and repair of tissue or organs. The large surface-area-to-volume ratio is one of the unique properties of nanofi brous mats. This paper gives a brief overview of possible materials and applications of nanofi brous mats for wound dressing.

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Nanomaterials from bacterial cellulose for antimicrobial wound dressing

Cited by 53 publications

References 26 publications

Bacterial cellulose: a versatile biopolymer for wound dressing applications

Bacterial cellulose: a versatile biopolymer for wound dressing applications

Bio-hybridization of nanobactericides with cellulose films for effective treatment against members of ESKAPE multi-drug-resistant pathogens

Review of Possible Applications of Nanofibrous Mats for Wound Dressings

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