Nanotechnology grabbed wide-reaching attention due to its incomparable and versatile uses and applications. Waste is emerging as the preeminent concern among researchers, industries, and other stakeholders. Although various attempts have already been done and are still improvising. Presently, the unpredictable interactions of nanomaterials (NMs) waste with other natural and synthetic components may lead to disastrous fallouts. This chapter will encapsulate the informative structure of nanomaterial-based wastes categorically and the possible, existing treatment technologies available. This chapter will also add a notable amount of knowledge of "Then, Now and Beyond" about the NMs wastes. The fate of the recovered wastes like reuse and reduce technology will also be discussed in this chapter. Nanotechnology is the most promising technology but the hidden facts are undiscussed or not discovered yet in the available literature. This also provokes the researchers to focus on the undiscovered part of NMs wastes and upgrading the existing technologies. NMs wastes are generated through the different phases like at the time of manufacturing of NMs, during the use and reuse of the NMs, or the waste generated after the end of the use of NMs/by-products out of production. This chapter will be helpful to know about the "cradle to grave" information about the NMs.