Nanoengineered oxygen-releasing polymeric scaffold with sustained release of dexamethasone for bone regeneration
Aatikaben Vahora,
Hemant Singh,
Aniruddha Dan
et al.
Abstract:Maintaining the continuous oxygen supply and proper cell growth before blood vessel ingrowth at the bone defect site are considerably significant issues in bone regeneration. Oxygen-producing scaffolds can supply oxygen and avoid hypoxia leading to expedited bone regeneration. Herein, first oxygen-producing calcium peroxide nanoparticles (CPO NPs) are synthesized, and subsequently, the various amounts of synthesized CPO NPs (0.1, 0.5, and 1wt/v%) loaded in the scaffold composite, which is developed by simple p… Show more
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