Nanodiagnostics in microbiology and dentistry

Subramani, Karthikeyan; Mehta, Manjula

doi:10.1016/b978-0-12-812291-4.00019-4

Cited by 17 publications

(7 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Carbon nanotubes are a class of nanomaterials, consisting of graphite sheets tubes with nano-scaled diameters. Carbon nanotubes can be single-walled or multi-walled, with open ends or closed with fullerene caps [90]. Recently, they have gained a great interest as nanocarrier systems, due to the possibility of functionalization with specific chemical compounds, thus modifying their physical and biological properties.…”

Section: Nanotechnology Approaches For Crossing the Blood-brain Bamentioning

confidence: 99%

Blood-Brain Delivery Methods Using Nanotechnology

et al. 2018

View full text Add to dashboard Cite

Pathologies of the brain, of which brain cancer, Alzheimer’s disease, Parkinson’s disease, stroke, and multiple sclerosis, are some of the most prevalent, and that presently are poorly treated due to the difficulties associated with drug development, administration, and targeting to the brain. The existence of the blood-brain barrier, a selective permeability system which acts as a local gateway against circulating foreign substances, represents the key challenge for the delivery of therapeutic agents to the brain. However, the development of nanotechnology-based approaches for brain delivery, such as nanoparticles, liposomes, dendrimers, micelles, and carbon nanotubes, might be the solution for improved brain therapies.

show abstract

Section: Nanotechnology Approaches For Crossing the Blood-brain Bamentioning

confidence: 99%

Blood-Brain Delivery Methods Using Nanotechnology

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Carbon nanotubes are the most commonly used among the class of carbon-based nanomaterials, comprising graphite sheets rolled into tubes with diameters within the nanoscale. Depending on their architecture, carbon nanotubes can be single-walled or multi-walled, with open ends or closed with fullerene caps [62]. Carbon nanotubes have gained great scientific attention in various fields owing to their unique structure, exceptional electrical, mechanical, optical, and thermal properties, and high surface area [63,64].…”

Section: Nanocarriers For Brain Targetingmentioning

confidence: 99%

Neuronanomedicine: An Up-to-Date Overview

et al. 2019

View full text Add to dashboard Cite

The field of neuronanomedicine has recently emerged as the bridge between neurological sciences and nanotechnology. The possibilities of this novel perspective are promising for the diagnosis and treatment strategies of severe central nervous system disorders. Therefore, the development of nano-vehicles capable of permeating the blood–brain barrier (BBB) and reaching the brain parenchyma may lead to breakthrough therapies that could improve life expectancy and quality of the patients diagnosed with brain disorders. The aim of this review is to summarize the recently developed organic, inorganic, and biological nanocarriers that could be used for the delivery of imaging and therapeutic agents to the brain, as well as the latest studies on the use of nanomaterials in brain cancer, neurodegenerative diseases, and stroke. Additionally, the main challenges and limitations associated with the use of these nanocarriers are briefly presented.

show abstract

“…(17,18) However, data issues such as low data volume, high sparsity and poor data quality can limit the efficacy of deep learning methods. (19)(20)(21)(22)(23)(24) Finally, it should be emphasized that ML use goes beyond decision-making systems and can be used in many medical applications such as Nanobots (miniscule robots used to perform specific tasks such as drug delivery (25) and in the assistance of impaired patients. These applications, while interesting, lie outside the scope of this work.…”

Section: Basic Definitionsmentioning

confidence: 99%