Nanocomposites based on biocompatible polymers and graphene oxide for antibacterial coatings

Abstract

Recently, antibacterial coatings based on graphene oxide (GO) nanocomposites have attracted many studies around the world. The use of polymers as the matrices of GO nanofillers in the nanocomposites has been explored to produce efficient coatings against bacteria. One of the most prospective applications is the incorporation of GO into biocompatible polymers, which can produce antibacterial coatings. Here, recent progresses on the antibacterial coatings of nanocomposites based on biocompatible polymers and GO are reviewed. The effect of GO filler concentrations, biocide materials, and biocompatibility are discussed to find the most efficient antibacterial activity and biocompatibility of nanocomposites. Among biocompatible polymers, chitosan (Cs), poly vinyl alcohol (PVA), and poly lactic acid (PLA) are the most popular matrices used for the nanocomposites. This review also elaborates challenges in the use of other biocompatible polymers. Future works on biocompatible antibacterial coatings should be conducted by considering the concentration of GO nanofillers or adding other materials such as essential oils to suppress the toxicity toward functional cells.

An overview of substrate stiffness guided cellular response and its applications in tissue regeneration

“…Incorporation of inorganic bioactive fillers, including calcium phosphates [ 53 , 87 ], silicate [ 88 ], BG [ 89 ], CNT [ 90 ], and graphene [ 91 ], into polymeric substrates has been prepared with an emphasis on the fabrication of hybrid biocomposites with tunable stiffness, as well as the adjustment of biological performance. As one of the primary components of bone ECM, calcium phosphates, mainly in the form of HAp [ 53 , 92 ], have been widely used as osteoinductive fillers in bone substrates due to their high strength and outstanding osteoconductivity.…”

Graphene Oxide/Polylactic Acid-Based Face Mask to Combat H3N2: A Strategy against Influenza

“…The antibacterial/antiviral behavior of graphene oxide has been previously reported, 26 and the main advances are summarized in Table 1. Recently, with the emergence of the COVID-19 pandemic, GO application as antivirals has broadly 27 showed that GO can exhibit significant antiviral properties even at a low concentration (1.5 μg/mL), which may be attributed to the negative charge and nanosheet structure, which was further demonstrated for SARS-CoV-2 variants by other authors.…”

“…The antibacterial/antiviral behavior of graphene oxide has been previously reported, 26 and the main advances are summarized in Table 1. Recently, with the emergence of the COVID-19 pandemic, GO application as antivirals has broadly increased.…”

A Triboelectric Nanocomposite for Sterile Sensing, Energy Harvesting, and Haptic Diagnostics in Interventional Procedures from Surgical Gloves

“…Second, the sensors and their components need to maintain sterility. Antimicrobial nanocomposites offer a promise to this end; [ 9 ] however, flexible, glove‐integrated antimicrobial sensors remain to be introduced. In fact, concerns about sterility may be avoided if the sensors are still functional even when mounted on a glove underneath a second sterile glove worn on top.…”