Nanocomposite: An emerging tool for bone tissue transplantation and drug delivery

Nanoparticles as Carriers in Medical Applications: A Review Focusing on the Preparation and Use of Nanoparticles in Tissue Regeneration

“…To achieve this, NPs are widely investigated as drug delivery vehicles due to their small size and large surface area/volume ratio to enable rapid release, ability to be actively targeted, and small degradation footprint (in case of An important issue to be considered in TERM strategies is the colonization of microorganisms on implants or materials used for regenerative treatment. This colonization leads to infections and disruption of the healing process [25]. Moreover, it can result in the formation of a "biofilm" which may provide an ideal environment for the propagation of resident flora.…”

“…The ones used most frequently include poly (lactic-co-glycolic acid) (PLGA), polyvinyl alcohol (PVA), alginates, polyethylene glycol (PEG), etc. [25,74]. Stabilizer: Compound that interacts with the growing NPs to determine its size, usually limiting it.…”

Synthesis and Microstructure Characterization of Novel Sr-HA Prepared by Co-precipitation with Enhanced Bioactivity

“…It plays an integral role in locomotion, ensures the skeleton has adequate load-bearing capacity, and acts as a protective casing for the delicate internal organs of the body. In addition to these structural functions, bone is intimately involved in homeostasis through its storage of Ca and P ions and by regulating the concentration of key electrolytes in the blood (6) . Beside Ca and P, bone apatite is substituted by many different trace elements occurring in smaller concentration.…”