Nanocellulose- based biosensor for colorimetric detection of glucose

Neubauerova, Katrin; Carneiro, Mariana C.C.G.; Rodrigues, L. R.; Moreira, Felismina T.C.; Sales, M. Goreti F.

doi:10.1016/j.sbsr.2020.100368

Cited by 30 publications

(31 citation statements)

References 60 publications

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“…For instance, the use of the oxidant agent 2,2,6,6tetramethylpiperine-1-oxyl (TEMPO) as a mediator in the oxidation process is a widely used and promising procedure. 58,192,195 It enables oxidation of primary hydroxyl groups from cellulose in aldehydes, which are further converted (using other reagents) into charged carboxyl groups. 235,236 The process is advantageous for being one-step and specific for primary alcohol groups of polysaccharides, keeping secondary ones unaffected.…”

Section: Nanomaterials In Sensorsmentioning

confidence: 99%

“…In another strategy, Neubauerova et al 58 developed a glucose colorimetric biosensor using CNM deposited onto a cellulose paper substrate. Specifically, the authors used MCC as a cellulose source, which was oxidized using TEMPOmediated oxidation, leading to the formation of carboxylated groups at the cellulose surface.…”

Section: Nanomaterials In Sensorsmentioning

confidence: 99%

“…Such products are typically derived from the sulfuric acid treatment of bleached kraft wood fibers or cotton, followed by washing and spray-drying, reagglomerating the smaller cellulosic crystalline domains through hydrogen bonding, which results in particles with minimum dimensions of 1 μm (see Figure D 1 ) . MCC has been used as the starting material of several pioneering studies in NC isolation. − …”

mentioning

confidence: 99%

“…Films exclusively constituted by CNM are so-called nanopaper, which can show optical transparency if the cellulose nanofibers are densely packed and the interstices between the fibers are small enough to avoid light scattering . In addition, the chemical composition and structure of foams, aerogels, and biofilms based on CNM can perform important roles in sensing and biosensing. − …”

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confidence: 99%

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A Review on the Role and Performance of Cellulose Nanomaterials in Sensors

et al. 2021

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Sensors and biosensors play a key role as an analytical tool for the rapid, reliable, and early diagnosis of human diseases. Such devices can also be employed for monitoring environmental pollutants in air and water in an expedited way. More recently, nanomaterials have been proposed as an alternative in sensor fabrication to achieve gains in performance in terms of sensitivity, selectivity, and portability. In this direction, the use of cellulose nanomaterials (CNM), such as cellulose nanofibrils (CNF), cellulose nanocrystals (CNC), and bacterial cellulose (BC), has experienced rapid growth in the fabrication of varied types of sensors. The advantageous properties are related to the supramolecular structures that form the distinct CNM, their biocompatibility, and highly reactive functional groups that enable surface functionalization. The CNM can be applied as hydrogels and xerogels, thin films, nanopapers and other structures interesting for sensor design. Besides, CNM can be combined with other materials (e.g., nanoparticles, enzymes, carbon nanomaterials, etc.) and varied substrates to advanced sensors and biosensors fabrication. This review explores recent advances on CNM and composites applied in the fabrication of optical, electrical, electrochemical, and piezoelectric sensors for detecting analytes ranging from environmental pollutants to human physiological parameters. Emphasis is given to how cellulose nanomaterials can contribute to enhance the performance of varied sensors as well as expand novel sensing applications, which could not be easily achieved using standard materials. Finally, challenges and future trends on the use of cellulose-based materials in sensors and biosensors are also discussed.

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Section: Nanomaterials In Sensorsmentioning

confidence: 99%

Section: Nanomaterials In Sensorsmentioning

confidence: 99%

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confidence: 99%

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confidence: 99%

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A Review on the Role and Performance of Cellulose Nanomaterials in Sensors

et al. 2021

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“…There are many approaches that have been developed in time to achieve a successful biosensor on cellulose-based substrates, 18 − 24 including cellulose of bacterial origin, 25 much before COVID-19, and they consist of immobilizing specific reagents on these substrates. Generally, this includes reagents that react with a given compound or group of compounds, 26 metal nanoparticles (NPs) with catalytic or plasmonic features 27 , 28 or selective biorecognition elements that capture a wide range of target analytes, 29 − 31 including disease diagnosis. 32 − 35 These events may be translated by monitoring alterations in optical features, 36 which may involve changes in maximum wavelength reflection/absorption 37 or the enhanced Raman-scattering properties.…”

Section: Introductionmentioning

confidence: 99%

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

et al. 2021

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The appearance and quick spread of the new severe acute respiratory syndrome coronavirus disease, COVID-19, brought major societal challenges. Importantly, suitable medical diagnosis procedures and smooth clinical management of the disease are an emergent need, which must be anchored on novel diagnostic methods and devices. Novel molecular diagnostic tools relying on nucleic acid amplification testing have emerged globally and are the current gold standard in COVID-19 diagnosis. However, the need for widespread testing methodologies for fast, effective testing in multiple epidemiological scenarios remains a crucial step in the fight against the COVID-19 pandemic. Biosensors have previously shown the potential for cost-effective and accessible diagnostics, finding applications in settings where conventional, laboratorial techniques may not be readily employed. Paper- and cellulose-based biosensors can be particularly relevant in pandemic times, for the renewability, possibility of mass production with sustainable methodologies, and safe environmental disposal. In this review, paper-based devices and platforms targeting SARS-CoV-2 are showcased and discussed, as a means to achieve quick and low-cost PoC diagnosis, including detection methodologies for viral genomic material, viral antigen detection, and serological antibody testing. Devices targeting inflammatory markers relevant for COVID-19 are also discussed, as fast, reliable bedside diagnostic tools for patient treatment and follow-up.

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Trending Technology of Glucose Monitoring during COVID‐19 Pandemic: Challenges in Personalized Healthcare

Phan

Hoang

et al. 2021

Adv Materials Technologies

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The COVID‐19 pandemic has continued to spread rapidly, and patients with diabetes are at risk of experiencing rapid progression and poor prognosis for appropriate treatment. Continuous glucose monitoring (CGM), which includes accurately tracking fluctuations in glucose levels without raising the risk of coronavirus exposure, becomes an important strategy for the self‐management of diabetes during this pandemic, efficiently contributing to the diabetes care and the fight against COVID‐19. Despite being less accurate than direct blood glucose monitoring, wearable noninvasive systems can encourage patient adherence by guaranteeing reliable results through high correlation between blood glucose levels and glucose concentrations in various other biofluids. This review highlights the trending technologies of glucose sensors during the ongoing COVID‐19 pandemic (2019–2020) that have been developed to make a significant contribution to effective management of diabetes and prevention of coronavirus spread, from off‐body systems to wearable on‐body CGM devices, including nanostructure and sensor performance in various biofluids. The advantages and disadvantages of various human biofluids for use in glucose sensors are also discussed. Furthermore, the challenges faced by wearable CGM sensors with respect to personalized healthcare during and after the pandemic are deliberated to emphasize the potential future directions of CGM devices for diabetes management.

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Nanocellulose- based biosensor for colorimetric detection of glucose

Cited by 30 publications

References 60 publications

A Review on the Role and Performance of Cellulose Nanomaterials in Sensors

A Review on the Role and Performance of Cellulose Nanomaterials in Sensors

Paper-Based Biosensors for COVID-19: A Review of Innovative Tools for Controlling the Pandemic

Trending Technology of Glucose Monitoring during COVID‐19 Pandemic: Challenges in Personalized Healthcare

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