Nanobiotics and the One Health Approach: Boosting the Fight against Antimicrobial Resistance at the Nanoscale

Abstract

Antimicrobial resistance (AMR) is a growing public health concern worldwide, and it poses a significant threat to human, animal, and environmental health. The overuse and misuse of antibiotics have contributed significantly and others factors including gene mutation, bacteria living in biofilms, and enzymatic degradation/hydrolyses help in the emergence and spread of AMR, which may lead to significant economic consequences such as reduced productivity and increased health care costs. Nanotechnology offers a promising platform for addressing this challenge. Nanoparticles have unique properties that make them highly effective in combating bacterial infections by inhibiting the growth and survival of multi-drug-resistant bacteria in three areas of health: human, animal, and environmental. To conduct an economic evaluation of surveillance in this context, it is crucial to obtain an understanding of the connections to be addressed by several nations by implementing national action policies based on the One Health strategy. This review provides an overview of the progress made thus far and presents potential future directions to optimize the impact of nanobiotics on AMR.

Innovating Leishmaniasis Treatment: A Critical Chemist’s Review of Inorganic Nanomaterials

“…Indeed, the use of a plant-based approach can be a powerful tool in the context of One Health. By integrating the knowledge of pharmacists, chemists, biologists and biomedical professionals, the need of hazardous chemicals can be reduced, thus improving environmental friendliness. , However, the bioreduction of metal salts presents a reproducibility challenge for nanoparticle production due to their heterogeneous and variable compositions. Notably, there is a scarcity of studies combining antileishmanial drugs with metallic nanoparticles to form DDS.…”