Nano-sensors in Food Nanobiotechnology

Jafarizadeh‐Malmiri, Hoda; Sayyar, Zahra; Anarjan, Navideh; Berenjian, Aydin

doi:10.1007/978-3-030-05846-3_6

Cited by 12 publications

(14 citation statements)

References 19 publications

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“…In detail, the synthesis of Ti3C2 MXene followed the steps: (1) Preparing the Ti3AlC2 MAX phase. It was obtained through ball milling TiC, Ti, and Al powders in the molar ratio 2:1:1.2 respectively, for 5 h. Under argon flow, the resulting powder was then pressed into a pellet and sintered at 1350 °C for 4 h. The collected pellet after being milled back into powder was sieved through a 160-mesh sieve; (2) etching Al from Recent advances in nanotechnology have made it possible to synthesize functionalized nanomaterials for applications in electronics, sensing, biomedicines for disease diagnosis and control, drug delivery, and the food industry [28][29][30][31]. Due to the increased surface areas and the feasibility of controllable size and surface properties, nanomaterials such as nanofibers, nanowires, and nanoparticles provide great opportunities for the development of advanced sensing systems and portable device/instrumentation with improved sensitivity and selectivity [32][33][34][35][36][37][38].…”

Section: Ti3c2 Nanomaterial-based Sensor Preparationmentioning

confidence: 99%

2D Nanomaterial, Ti3C2 MXene-Based Sensor to Guide Lung Cancer Therapy and Management

et al. 2021

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Major advances in cancer control can be greatly aided by early diagnosis and effective treatment in its pre-invasive state. Lung cancer (small cell and non-small cell) is a leading cause of cancer-related deaths among both men and women around the world. A lot of research attention has been directed toward diagnosing and treating lung cancer. A common method of lung cancer treatment is based on COX-2 (cyclooxygenase-2) inhibitors. This is because COX-2 is commonly overexpressed in lung cancer and also the abundance of its enzymatic product prostaglandin E2 (PGE2). Instead of using traditional COX-2 inhibitors to treat lung cancer, here, we introduce a new anti-cancer strategy recently developed for lung cancer treatment. It adopts more abundant omega-6 (ω-6) fatty acids such as dihomo-γ-linolenic acid (DGLA) in the daily diet and the commonly high levels of COX-2 expressed in lung cancer to promote the formation of 8-hydroxyoctanoic acid (8-HOA) through a new delta-5-desaturase (D5Di) inhibitor. The D5Di does not only limit the metabolic product, PGE2, but also promote the COX-2 catalyzed DGLA peroxidation to form 8-HOA, a novel anti-cancer free radical byproduct. Therefore, the measurement of the PGE2 and 8-HOA levels in cancer cells can be an effective method to treat lung cancer by providing in-time guidance. In this paper, we mainly report on a novel sensor, which is based on a newly developed functionalized nanomaterial, 2-dimensional nanosheets, or Ti3C2 MXene. The preliminary results have proven to sensitively, selectively, precisely, and effectively detect PGE2 and 8-HOA in A549 lung cancer cells. The capability of the sensor to detect trace level 8-HOA in A549 has been verified in comparison with the traditional gas chromatography–mass spectrometry (GC–MS) method. The sensing principle could be due to the unique structure and material property of Ti3C2 MXene: a multilayered structure and extremely large surface area, metallic conductivity, and ease and versatility in surface modification. All these make the Ti3C2 MXene-based sensor selectively adsorb 8-HOA molecules through effective charge transfer and lead to a measurable change in the conductivity of the material with a high signal-to-noise ratio and excellent sensitivity.

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Section: Ti3c2 Nanomaterial-based Sensor Preparationmentioning

confidence: 99%

2D Nanomaterial, Ti3C2 MXene-Based Sensor to Guide Lung Cancer Therapy and Management

et al. 2021

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“…These materials have used to form impedimetric sensors for rapid, efficient and economical sensing [ 70 , 71 ]. Various type of nanomaterials has been considered [ 72 , 73 ] to form sensors with high sensitivity and selectivity. Some of the common ones are graphene [ 74 , 75 ], gold [ 76 , 77 ], and mono- and bimetallic nanoparticles and metallic nanocomposites [ 78 , 79 ].…”

Section: Type Of Impedimetric Sensors Utilized For the Inspection mentioning

confidence: 99%

A Review on the Use of Impedimetric Sensors for the Inspection of Food Quality

Yuan

Nag

et al. 2020

IJERPH

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This paper exhibits a thorough review of the use of impedimetric sensors for the analysis of food quality. It helps to understand the contribution of some of the major types of impedimetric sensors that are used for this application. The deployment of impedimetric sensing prototypes has been advantageous due to their wide linear range of responses, detection of the target analyte at low concentrations, good stability, high accuracy and high reproducibility in the results. The choice of these sensors was classified on the basis of structure and the conductive material used to develop them. The first category included the use of nanomaterials such as graphene and metallic nanowires used to form the sensing devices. Different forms of graphene nanoparticles, such as nano-hybrids, nanosheets, and nano-powders, have been largely used to sense biomolecules in the micro-molar range. The use of conductive materials such as gold, copper, tungsten and tin to develop nanowire-based prototypes for the inspection of food quality has also been shown. The second category was based on conventional electromechanical circuits such as electronic noses and other smart systems. Within this sector, the standardized systems, such as electronic noses, and LC circuit -based systems have been explained. Finally, some of the challenges posed by the existing sensors have been listed out, along with an estimate of the increase in the number of sensors employed to assess food quality.

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“…Choi et al [226] gave a still valid overview of the use of miniaturized sensors for immediate, so-called" point-of-care (POC) food safety analyses. These miniaturized sensing devices include: A book that was recently published by Jafarizadeh-Malmiri et al [227] has a focus on the benefits of the use of nanotechnology in the food industry, starting with food processing, packaging, transport, safety, and quality control. An overview of novel detection techniques based on the use of nanobiosensors in food industry and challenges and problems that relate to their use.…”

Section: Use Of Biosensors For Food Quality Controlmentioning

confidence: 99%

“…A discussion about abovementioned application was given elsewhere [2]. A new approach, namely the use of food-derived sensors based on biocompatible materials like polysaccharides, lipids, and proteins may be the right way to solve the main objection that still was not properly addressed in the book mentioned above [227,228].…”

Section: Use Of Biosensors For Food Quality Controlmentioning

confidence: 99%

“…A book that was recently published by Jafarizadeh‐Malmiri et al. [227] has a focus on the benefits of the use of nanotechnology in the food industry, starting with food processing, packaging, transport, safety, and quality control. An overview of novel detection techniques based on the use of nanobiosensors in food industry and challenges and problems that relate to their use.…”

Section: New Trends In Detection Of Foodborne Pathogensmentioning

confidence: 99%

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Biofilm formation and extracellular microvesicles—The way of foodborne pathogens toward resistance

Begić

Josić

2020

Electrophoresis

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Biofilm formation and extracellular microvesicles-The way of foodborne pathogens toward resistance Almost all known foodborne pathogens are able to form biofilms as one of the strategies for survival under harsh living conditions, to ward off the inhibition and the disinfection during food production, transport and storage, as well as during cleaning and sanitation of corresponding facilities. Biofilms are communities where microbial cells live under constant intracellular interaction and communication. Members of the biofilm community are embedded into extracellular matrix that contains polysaccharides, DNA, lipids, proteins, and small molecules that protect microorganisms and enable their intercellular communication under stress conditions. Membrane vesicles (MVs) are produced by both Gram positive and Gram negative bacteria. These lipid membrane-enveloped nanoparticles play an important role in biofilm genesis and in communication between different biofilm members. Furthermore, MVs are involved in other important steps of bacterial life like cell wall modeling, cellular division, and intercellular communication. They also carry toxins and virulence factors, as well as nucleic acids and different metabolites, and play a key role in host infections. After entering host cells, MVs can start many pathologic processes and cause serious harm and cell death. Prevention and inhibition of both biofilm formation and shedding of MVs by foodborne pathogens has a very important role in food production, storage, and food safety in general. Better knowledge of biofilm formation and maintaining, as well as the role of microbial vesicles in this process and in the process of host cells' infection is essential for food safety and prevention of both food spoilage and host infection.

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Nano-sensors in Food Nanobiotechnology

Cited by 12 publications

References 19 publications

2D Nanomaterial, Ti3C2 MXene-Based Sensor to Guide Lung Cancer Therapy and Management

2D Nanomaterial, Ti3C2 MXene-Based Sensor to Guide Lung Cancer Therapy and Management

A Review on the Use of Impedimetric Sensors for the Inspection of Food Quality

Biofilm formation and extracellular microvesicles—The way of foodborne pathogens toward resistance

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