Nano engineered biodegradable capsules for the encapsulation and kinetic release studies of ciprofloxacin hydrochloride

Novel Double Cross-Linked Acrylic Acid/Bagasse Cellulose Porous Hydrogel for Controlled Release of Citral and Bacteriostatic Effects

“…It could be seen that the Ritger–Peppas model had high fitting degrees for AA/BC-4C ( R 2 = 0.94036) and AA/BC-6C ( R 2 = 0.95518); thus, the Ritger–Peppas model could better reflect the release of citral molecules from the hydrogels. In addition, n ≤ 0.45 demonstrated that the release of citral molecules corresponded to Fickian (diffusion-controlled) release; it means that citral molecules migrated from a high-concentration region to a low-concentration region instead of the effect of skeleton dissolution. , According to the fitting model, the release time of citral was calculated to be around 2 days. It was indicated that the hydrogel inclusion compounds could release active substances for a long time, which laid a foundation for preservation applications.…”

“…In order to elucidate the release mechanism of citral molecules embedded in hydrogels, four release kinetic models including zero-order, first-order, Higuchi, and Ritger–Peppas were tested to fit the release curves. − The equations of four kinetic models are represented by eqs –. Y = k 0 t + Y 0 Y = k 1 ( 1 − e ( − k 2 t ) ) Y = k t 1 / 2 Y = k t t n where Y denotes the release rate of citral (%), t is the release time (min), k is the release rate constant, and n is the diffusional exponent.…”