Nano-encapsulation of catechin in starch nanoparticles: Characterization, release behavior and bioactivity retention during simulated in-vitro digestion

Ahmad, Mudasir; Mudgil, Priti; Gani, Adil; Hamed, Fathalla; Masoodi, F. A.; Maqsood, Sajid

doi:10.1016/j.foodchem.2018.07.024

Cited by 253 publications

(132 citation statements)

References 40 publications

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“…This also indicates that major peaks of diffraction do not exist and whole structure appeared like amorphous hump. Similar results were obtained from our previous studies where there is decrease in crystallite size of starch after sonication and alkalization of starch 3 . Methods like gamma irradiation, heat moisture treatment, microwave degradation and ultrasonic degradation have also shown decrease in crystallinity and crystallite size of starch 3,29-32 .…”

Section: Resultssupporting

confidence: 91%

“…Combined treatment of NaOH and ultra-sonication was suggested to play a significant role in a major change in the starch nanoparticles resulting in surface erosion, with notch and groove formation, breaking the cell walls to generate the smaller fragment and smaller sphere 36 . The granular structure of the native starch particles was smooth and round or oval shaped as was also reported in our previous studies 3,5,6,18 . The micrographs revealed that starch nano-particle granules are irregular in shape, size with no uniform pattern, which has been ascribed to the cavitation phenomenon inducing very high pressures and shear forces responsible for degradation of the external crystalline and amorphous layers of starch granules and therefore small segments can be produced.…”

Section: Resultssupporting

confidence: 85%

“…The samples of HS, WS and LS were cut into small pieces after de-hulling/peeling and then grounded along with some quantity of water in a domestic blender. The starch has been extracted using the alkaline steeping method 3 .…”

Section: Discussionmentioning

confidence: 99%

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Production and characterization of starch nanoparticles by mild alkali hydrolysis and ultra-sonication process

Ahmad

Gani

Hassan

et al. 2020

Sci Rep

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138

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in this report, synthesis of the starch nanoparticles from underutilized and cheap sources viz: Horse chestnut (HS), Water chestnut (WS) and Lotus stem (LS) by using mild alkali hydrolysis and ultrasonication process has been presented. The particles were characterized by Differential scanning colorimeter (DSC), X-Ray Diffraction (XRD), Rheology, Scanning electron microscopy (SEM) and Fourier transform infra-spectroscopy (AtR-ftiR). the particle size measurements, functional properties and antioxidant potential of starch nanoparticles were also analyzed. the experimental results revealed that the average particle size diameter of Horse chestnut starch nanoparticles (HSp), Water chestnut starch nanoparticles (WSP) and Lotus stem starch nanoparticles (LSP) was found to be 420, 606 and 535 nm, respectively. We observed a notable increase in the water absorption capacity but decreased capacity for oil absorption in the starch nano-particles. SeM images revealed damaged starch granules after size reduction. Additionally, loss of crystallinity and molecular order was observed from XRD and AtR-ftiR spectra. it was concluded that the starch nanoparticles have better thermal stability, increased viscosity and antioxidant properties. Starch is a natural biopolymer, which is abundantly found in nature and also major component of our daily diet. It is mainly found in plant roots, staple crops and cereals such as rice, maize, wheat, barley, corn, tapioca, potato and others 1. Starch is composed of linear chain molecule; amylose and branched chain molecule; amylopectin. These two starch components are assembled in the form of granules with the size ranging from 1 to 100 µm 2. Starch has various applications, it has been used as thickening, gelling, stabilizing in a wide variety of foods and non-food products 3,4. Starch is also used for drug and bioactive delivery systems 3,5,6. The native form has however many limitations such as poor solubility, retro-gradation, limited digestibility and poor functional properties. For this reason, various physical, chemical and enzymatic methods have been employed to reduce these limitations or to add new attributes. Currently, starch nano particles are gaining more interest for improved quality and wide applications. They have been considered as the promising biomaterials for novel utilization in foods, cosmetics, and medicines as well as various composites 7. There are various techniques for starch nano particle preparations including hydrolysis by acid, enzymes or combination of two, regeneration and mechanical treatments using extrusion, irradiation, ultrasound or precipitation by co solvent 3,8. The easy and cost-effective methods for starch and starch derivative nanoparticles are always of paramount importance. Among various such methods, nano-precipation and ultra-sonication are very simple and reliable methods for nanoparticle production with desired size. The precipitation process involves a drop wise addition of a dilute starch solution into a non-solvent and ultra-sonication redu...

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Section: Resultssupporting

confidence: 91%

Section: Resultssupporting

confidence: 85%

See 1 more Smart Citation

Production and characterization of starch nanoparticles by mild alkali hydrolysis and ultra-sonication process

Ahmad

Gani

Hassan

et al. 2020

Sci Rep

Self Cite

138

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“…The encapsulation process also induced significant changes in the physical properties. A higher negative zeta potential (−34.4 mV) was displayed in HM, which is responsible for electrostatic repulsion and is strongly related to the stability of microcapsule formulation . Furthermore, HM was identified with significantly reduced moisture and hygroscopic content, which, according to previous studies, may affect the storage stability of microcapsules because polymer carriers change from a glassy to an amorphous state with higher moisture content, resulting in the release and degradation of core material .…”

Section: Resultsmentioning

confidence: 72%

Stabilisation and detoxification of henna (Lawsonia inermis L.) extract for hair dye cosmetics by spray‐drying encapsulation

Tang

Yang

et al. 2019

Coloration Technology

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Henna (Lawsonia inermis L.) leaves have been widely used as a natural plant colorant for hair dyeing and body art. However, the utilisation of henna dye extract in commercial colour cosmetics is compromised by its potential harmful effects to humans. This study demonstrates that spray‐drying encapsulation using maltodextrin and gum arabic as biocompatible polymeric carriers can be used as a promising strategy to detoxify henna dye extract while maintaining its hair dyeing efficiency for cosmetics. Henna extract‐loaded microcapsules with an average particle size of 4.1 μm were prepared with an excellent encapsulation efficiency (98.4%) and a negative zeta potential (−34.4 mV). The morphology and physicochemical properties of the microcapsules were characterised by comparison with a spray‐dried sample of neat henna extract. The in vitro toxicological results showed that the microencapsulation process significantly reduced the contact toxicity of henna extract towards human epidermal keratinocytes as well as to the eyes and skin. The encapsulated henna extract also exhibited improved storage stability at three different temperatures (4, 25 and 50°C) for 14 days. Furthermore, the microcapsules demonstrated satisfactory hair dyeing efficiency as natural colorants with good colour fastness towards light and washing.

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“…The encapsulation efficiency (EE) of the encapsulation process was calculated according to the procedure described by Paramera, Konteles, and Karathanos (), Poomkokrak, Niamnuy, Choicharoen, and Devahastin () and Ahmad et al (). Then the percentage of encapsulation efficiency (%EE) as the ratio of the quantity of encapsulated phenolic compounds over its total quantity initially added was shown in the Equation (1).…”

Section: Methodsmentioning

confidence: 99%

Effect of different coating materials on freeze‐drying encapsulation of bioactive compounds from fermented tea leaf wastewater

Ravichai

Muangrat

2019

J Food Process Preserv

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Bioactive compounds present in concentrated fermented Miang wastewater (CFMW) were encapsulated by freeze drying using various coating materials (maltodextrin, gum arabic, and modified starch) and CFMW‐to‐coating material ratios. The highest encapsulation efficiency of 98.05% was produced with gum arabic coating and 10:1 CFMW‐to‐coating ratio. The encapsulated Miang powder contained gallocatechin, epigallocatechin, catechin, epicatechin, gallic acid, and caffeine content of approximately 8.33, 27.81, 76.53, 8.01, 4.44, and 257.47 mg/100 g dry Miang powder (DMP), respectively. The antioxidant values (IC50) of the Miang powder were 22.44 µg/ml against DPPH radicals and 334.33 µg/mL against ABTS radicals. Similarly to the freeze‐dried sample, spray‐dried Miang powder formulated with gum arabic coating, which were prepared for comparison, achieved the encapsulation efficiency 85.18%, total catechins 105.22 mg/100 g DMP, DPPH IC50 value 21.88 µg/ml and ABTS IC50 value 366.32 µg/ml. Additionally, the encapsulated Miang powder could be utilized to enhance the value of low‐quality tea drink. Practical applications The wastewater from fermented tea leaf (Miang) production is an interesting natural source of phenolic compounds, including the antioxidants gallocatechin, epigallocatechin, catechin, epicatechin, and gallocatechin gallate. Freeze drying with gum arabic as a coating material can be utilized to encapsulate these bioactive compounds present in the wastewater of fermented Miang with high encapsulation efficiency. Encapsulated Miang powder could be used to enhance the value of low‐quality tea drink. Therefore, encapsulated Miang powder is a natural bioactive compound source with the potential as an ingredient in food and beverage production.

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Nano-encapsulation of catechin in starch nanoparticles: Characterization, release behavior and bioactivity retention during simulated in-vitro digestion

Cited by 253 publications

References 40 publications

Production and characterization of starch nanoparticles by mild alkali hydrolysis and ultra-sonication process

Production and characterization of starch nanoparticles by mild alkali hydrolysis and ultra-sonication process

Stabilisation and detoxification of henna (Lawsonia inermis L.) extract for hair dye cosmetics by spray‐drying encapsulation

Effect of different coating materials on freeze‐drying encapsulation of bioactive compounds from fermented tea leaf wastewater

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