Nano-enabled sensing of per-/poly-fluoroalkyl substances (PFAS) from aqueous systems – A review

Garg, Shafali; Kumar, Pankaj; Greene, George W.; Mishra, Vandana; Avisar, Dror; Sharma, Raghav; Dumée, Ludovic F.

doi:10.1016/j.jenvman.2022.114655

Cited by 30 publications

(16 citation statements)

References 183 publications

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“…Recent efforts in biosensing applications are also focused on the use of binding proteins or protein bioreceptors for the detection of PFAS (Moro et al, 2020;Daems et al, 2021;Mann et al, 2022;Kowalska et al, 2023). The development of biosensors for PFAS detection, particularly in complex food matrices remains a challenge, as current efforts for end-product sensor development in the field focus heavily on water samples as their target analyte (Rodriguez et al, 2020;Garg et al, 2022).…”

Section: Pfas Analytical Methodsmentioning

confidence: 99%

In light of the new legislation for per- and polyfluoroalkyl substances, can continued food sustainability be achieved?

Senovilla-Herrero,

Moore,

Service

et al. 2024

Front. Sustain. Food Syst.

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Per- and polyfluoroalkyl substances (PFAS) are a group of persistent organic pollutants which pose significant risks to human health and the environment. This article comprehensively examines the implications of new legislation concerning PFAS for food sustainability. The current legislative frameworks governing PFAS in food production and distribution are explored, highlighting the need for robust mitigation strategies to safeguard food safety and environmental integrity. It delves into the challenges posed by the legislation, raising questions about the balance between environmental protection and the sustainability of the food system. It provides a review of the state-of-the-art analytical methods for PFAS detection and quantification in water and food matrices. Their advantages and limitations are discussed, offering valuable insights for researchers in the field. In addition, a range of mitigation strategies to combat PFAS contamination in the food supply chain are explored. By collating current knowledge on PFAS contamination in sustainable food systems, this article aims to provide a comprehensive resource for researchers, policymakers, and practitioners striving to ensure the safety and sustainability of our global food supply. The integration of legislative insights, advanced analytical techniques, and practical mitigation approaches offers a holistic perspective on managing PFAS-related challenges in the context of sustainable food systems.

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Section: Pfas Analytical Methodsmentioning

confidence: 99%

In light of the new legislation for per- and polyfluoroalkyl substances, can continued food sustainability be achieved?

Senovilla-Herrero,

Moore,

Service

et al. 2024

Front. Sustain. Food Syst.

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“…Biosensors are prepared using either biological materials such as enzymes or biomimetic substances such as molecularly imprinted polymers (MIPs) as bioreceptors to selectively identify and bind with the target compound. 30 Enzymes are biological catalysts that drive and facilitate biochemical reactions within the living cell. 31 Molecularly imprinted polymers are synthetic analogs to the natural antibody− antigen systems which work on lock and key mechanisms.…”

Section: Hydrogen Biosensingmentioning

confidence: 99%

“…Usually, there is an electron ionization ion source and a quadrupole analyzer, which monitors the molecular ion (H + ) of the protonated carrier gas (N 2 ) . Such techniques are highly accurate and offer extremely low limits of detection of up to ppb levels, however, these involve arduous and drawn-out sample preparation, expensive equipment, manpower, trained personnel, and long processing times . These techniques are often ex situ , and recently, the demand for in situ and real-time sensing has given way to the development of mobile, facile, and extremely sensitive (∼1 ppb LOD) sensors …”

Section: Benchmarking With Other Hydrogen Detection Techniquesmentioning

confidence: 99%

Hydrogen Biosensing: Prospects, Parallels, and Challenges

Garg

Mishra

Vega

et al. 2023

Ind. Eng. Chem. Res.

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The implementation of hydrogen, as a renewable and clean energy source, has the potential to replace fossil fuels and to decarbonize hard-to-abate sectors, enabling sustainable development with a lower environmental footprint. At concentrations higher than 4 vol %, hydrogen is, however, highly flammable and real-time monitoring and detection are required to ensure safe operation during production, storage, transportation, and utilization of it. Hydrogen sensors shall, therefore, be both efficient and sensitive to operate across a wide range of concentrations and mixtures with other gases. Current commercial hydrogen sensors are primarily dependent on electrochemical, heat-conductance, or calorimetric technologies, being intrinsically developed from noble and expensive metals or complex setups. Portable hydrogen sensing technologies for personal protective equipment in remote and confined areas shall, however, require them to be selective and specific, light weight, and mobile, as well as self-regenerating and stable for the long-term. An emerging type of hydrogen sensor involves biosensing through biological pathways whereby hydrogenase is extracted from microbial communities and used for carrying out the reversible hydrogen oxidation reaction, allowing sensitivity down to 0.4 ppb in complex environments. Microbial communities innately use hydrogen for metabolic activities related to growth and energy synthesis. This review highlights the recent developments in hydrogen biosensing while presenting viable options for on-site and fast hydrogen detection, allowing timely action for mitigating risks related to hydrogen leakages and inflammation. Beyond discussing the mechanisms and materials used to generate hydrogen biosensors, a critical comparison with conventional hydrogen and other gaseous sensors is presented, highlighting the opportunities and remaining challenges in this field.

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“…Current US EPA methods for the detection of PFAS at the ng·L –1 range rely on combinations of liquid chromatography and mass spectroscopy. , Although these methods provide accuracy and sensibility, they are cost-prohibitive requiring specialized laboratories with well-trained personnel. Recent research efforts have been focused on developing fast, portable, user-friendly, low-cost detection methods that will allow for continuous environmental monitoring. ,− However, few sensors are suitable for on-site detection, and they further lack sufficient sensitivity and/or selectivity. In addition to the ultralow concentrations of PFAS in water, the complexity of real water samples, which usually contain various ions, biopolymers, humic acids, organic oils, or surfactants, makes PFAS detection, monitoring, and mitigation extremely challenging.…”

Section: Introductionmentioning

confidence: 99%

Ultratrace PFAS Detection Using Amplifying Fluorescent Polymers

2023

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Per-and poly(fluoroalkyl) substances (PFAS) are environmentally persistent pollutants that are of growing concern due to their detrimental effects at ultratrace concentrations (ng• L −1 ) in human and environmental health. Suitable technologies for on-site ultratrace detection of PFAS do not exist and current methods require complex and specialized equipment, making the monitoring of PFAS in distributed water infrastructures extremely challenging. Herein, we describe amplifying fluorescent polymers (AFPs) that can selectively detect perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) at concentrations of ng•L −1 . The AFPs are highly fluorinated and have poly(p-phenylene ethynylene) and polyfluorene backbones bearing pyridine-based selectors that react with acidic PFAS via a proton-transfer reaction. The fluorinated regions within the polymers partition PFAS into polymers, whereas the protonated pyridine units create lowerenergy traps for the excitons, and emission from these pyridinium sites results in red-shifting of the fluorescence spectra. The AFPs are evaluated in thin-film and nanoparticle forms and can selectively detect PFAS concentrations of ∼1 ppb and ∼100 ppt, respectively. Both polymer films and nanoparticles are not affected by the type of water, and similar responses to PFAS were found in milliQ water, DI water, and well water. These results demonstrate a promising sensing approach for on-site detection of aqueous PFAS in the ng•L −1 range.

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Nano-enabled sensing of per-/poly-fluoroalkyl substances (PFAS) from aqueous systems – A review

Cited by 30 publications

References 183 publications

In light of the new legislation for per- and polyfluoroalkyl substances, can continued food sustainability be achieved?

In light of the new legislation for per- and polyfluoroalkyl substances, can continued food sustainability be achieved?

Hydrogen Biosensing: Prospects, Parallels, and Challenges

Ultratrace PFAS Detection Using Amplifying Fluorescent Polymers

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