Nano-enabled personal care products: Current developments in consumer safety

Adawi, Hayat I.; Newbold, Morgan A.; Reed, Jasmine M.; Vance, Marina E.; Feitshans, Ilise L.; Bickford, Lissett R.; Lewinski, Nastassja A.

doi:10.1016/j.impact.2018.08.002

Cited by 32 publications

(11 citation statements)

References 81 publications

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“…The second source of MNPs is plastic debris that degrades from the large pieces of plastics due to UV radiation, physical wear, and biodegradation in the environment [ 11 – 13 , 17 , 24 , 49 ]. After plastics enter the environment, they are exposed to UV radiation that catalyzes the photo-oxidation of plastics, making them brittle.…”

Section: Mnps In the Environmentmentioning

confidence: 99%

“…After plastics enter the environment, they are exposed to UV radiation that catalyzes the photo-oxidation of plastics, making them brittle. Upon further interactions with the wind, waves, and other abrasive interactions, the structural integrity of the plastics further weakens, and MNPs are formed and released from the plastic surface through delamination [ 9 , 11 – 13 , 16 , 17 , 24 , 49 – 52 ]. These results indicate that both MPs and NPs can be produced in the degradation process of disposable plastic waste and accumulate over time [ 18 , 53 , 54 ].…”

Section: Mnps In the Environmentmentioning

confidence: 99%

“…After entering the environment, interactions between the plastic waste and environmental components can degrade large pieces of plastics to smaller plastic debris [8][9][10]. In addition, tiny plastic particles are commonly manufactured already and added to consumer products such as personal care products that are discarded after use, leading to another important direct source of plastic pollution in the environment [11][12][13]. According to the diameter of plastic fragments or particles, plastic particles can be divided into microplastics (MPs) and nanoplastics (NPs), with MPs being less than 5 mm in diameter and NPs being 1 to 100 or 1000 nm in diameter [14][15][16][17][18][19].…”

Section: Introductionmentioning

confidence: 99%

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Health impacts of environmental contamination of micro- and nanoplastics: a review

Jiang

Kauffman

et al. 2020

Environ Health Prev Med

230

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Plastics are extensively used in our daily life. However, a significant amount of plastic waste is discharged to the environment directly or via improper reuse or recycling. Degradation of plastic waste generates micro-or nanosized plastic particles that are defined as micro-or nanoplastics (MNPs). Microplastics (MPs) are plastic particles with a diameter less than 5 mm, while nanoplastics (NPs) range in diameter from 1 to 100 or 1000 nm. In the current review, we first briefly summarized the environmental contamination of MNPs and then discussed their health impacts based on existing MNP research. Our review indicates that MNPs can be detected in both marine and terrestrial ecosystems worldwide and be ingested and accumulated by animals along the food chain. Evidence has suggested the harmful health impacts of MNPs on marine and freshwater animals. Recent studies found MPs in human stool samples, suggesting that humans are exposed to MPs through food and/or drinking water. However, the effect of MNPs on human health is scarcely researched. In addition to the MNPs themselves, these tiny plastic particles can release plastic additives and/or adsorb other environmental chemicals, many of which have been shown to exhibit endocrine disrupting and other toxic effects. In summary, we conclude that more studies are necessary to provide a comprehensive understanding of MNP pollution hazards and also provide a basis for the subsequent pollution management and control.

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Section: Mnps In the Environmentmentioning

confidence: 99%

Section: Mnps In the Environmentmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Health impacts of environmental contamination of micro- and nanoplastics: a review

Jiang

Kauffman

et al. 2020

Environ Health Prev Med

230

View full text Add to dashboard Cite

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“…The median global production of TiO 2 (3000 tons/year) and ZnO (550 tons/year) exceeds that of Ag (55 tons/year) [62]. The FDA and large cosmetic companies claim that the chemicals commonly used in beauty products (e.g., parabens, sodium lauryl sulfate, petrolatum, phthalates, synthetic polymers, synthetic fragrances) are safe in small amounts, but none have long-term benefits.…”

Section: Sustainability Aspects Of Cosmetic Productsmentioning

confidence: 99%

Characterization of Inhalable Aerosols from Cosmetic Powders and Sustainability in Cosmetic Products

Sohn

Kim

2020

Sustainability

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Consumers may be exposed to aerosols that penetrate the lungs while applying cosmetics in a powder form. Toxic ingredients contained in aerosols can have a detrimental effect on the respiratory system. Two types of cosmetic powders were selected to evaluate the quantitative exposure of aerosols released from facial and eyeshadow products for five minutes. Scanning electron microscopy and energy-dispersive X-ray spectroscopy were used to analyze the morphology of the cosmetic particles and to measure the inorganic components in the related aerosol. Deposition fractions were calculated using the International Commission on Radiological Protection model to evaluate the deposition patterns in the regions based on the respiratory tract. The aerosol dosage was calculated from the aerosol concentrations. For all cosmetic powders, 78% of aerosol deposition occurred in the head airways, while less than 2.5% was deposited in the tracheobronchial region, and less than 1% was deposited in the alveolar regions. The calculated dosage for this study was 700 µg for PM10 and 200 µg for PM2.5. This study presents a strategy for improving the sustainability of the cosmetic industry by providing a model for the quantitative evaluation and respiratory-based deposition of aerosols released from cosmetic powders.

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“…When manufacturing new products that contain engineered nanomaterials (ENM), often referred to as nano-enabled products [ 1 ], in addition to improving product functionality and quality, the safety of the products for the user as well as safe manufacturing (safety of workers) must be ensured. The topic of safe-by-design (SbD) is therefore gaining more and more importance in the field of nanotechnology [ 2 , 3 , 4 , 5 ].…”

Section: Introductionmentioning

confidence: 99%

Influence of Physicochemical Characteristics and Stability of Gold and Silver Nanoparticles on Biological Effects and Translocation across an Intestinal Barrier—A Case Study from In Vitro to In Silico

et al. 2021

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A better understanding of their interaction with cell-based tissue is a fundamental prerequisite towards the safe production and application of engineered nanomaterials. Quantitative experimental data on the correlation between physicochemical characteristics and the interaction and transport of engineered nanomaterials across biological barriers, in particular, is still scarce, thus hampering the development of effective predictive non-testing strategies. Against this background, the presented study investigated the translocation of gold and silver nanoparticles across the gastrointestinal barrier along with related biological effects using an in vitro 3D-triple co-culture cell model. Standardized in vitro assays and quantitative polymerase chain reaction showed no significant influence of the applied nanoparticles on both cell viability and generation of reactive oxygen species. Transmission electron microscopy indicated an intact cell barrier during the translocation study. Single particle ICP-MS revealed a time-dependent increase of translocated nanoparticles independent of their size, shape, surface charge, and stability in cell culture medium. This quantitative data provided the experimental basis for the successful mathematical description of the nanoparticle transport kinetics using a non-linear mixed effects modeling approach. The results of this study may serve as a basis for the development of predictive tools for improved risk assessment of engineered nanomaterials in the future.

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Nano-enabled personal care products: Current developments in consumer safety

Cited by 32 publications

References 81 publications

Health impacts of environmental contamination of micro- and nanoplastics: a review

Health impacts of environmental contamination of micro- and nanoplastics: a review

Characterization of Inhalable Aerosols from Cosmetic Powders and Sustainability in Cosmetic Products

Influence of Physicochemical Characteristics and Stability of Gold and Silver Nanoparticles on Biological Effects and Translocation across an Intestinal Barrier—A Case Study from In Vitro to In Silico

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