Abstract:Nanoparticles in the single digit nanometer range can be easily isolated and studied with low optical powers using nanoaperture tweezers. We have studied individual proteins and their interactions with small molecules, DNA and antibodies. Recently, using the fluctuations of the trapped object, we have pioneered a new way to "listen" to the vibrations of nanoparticles in the 100 GHz -1 THz range; the approach is called extraordinary acoustic Raman (EAR). EAR gives unprecedented low frequency spectra of individu… Show more
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