Nano-bio interactions of 2D molybdenum disulfide

MoS2 nanosheet induced destructive alterations in the Escherichia coli bacterial membrane

“…16 Molybdenum disulfide (MoS 2 ), a representative member of the 2D TMD class, is widely utilized in several therapeutic and bioengineering applications. 17 To name a few, its application domain includes MoS 2 assisted drug delivery, 18,19 as a nanoprobe for biomolecule detection, 20 in cancer therapies 18,21 and as an antibacterial agent for rapid water disinfection. 22 It comprises of a three layered structure with a monolayer of molybdenum (Mo) atoms sandwiched between two parallel sulphur (S) layers.…”

MoS2 nanosheets effectively bind to the receptor binding domain of the SARS-CoV-2 spike protein and destabilize the spike–human ACE2 receptor interactions

“…15,16 These nanomaterials are easy to synthesize and are biocompatible possessing a large surface area to trap microbes. 17,18 Nanosheets have the capacity to cause physical impediments such as cleaving bacterial membranes and inducing oxidative stress in cells 18 without the generation of resistance, [19][20][21] thereby making them an effective alternative to antibiotics and conventional nanoparticles. 22 Recently, graphene-based nanosheets and their derivatives have been exploited against SARS-CoV-2 due to their undeniable potential as an antimicrobial agent.…”

A novel electrochemical immunosensor based on PdAgPt/MoS2 for the ultrasensitive detection of CA 242

“…Currently, the common load materials include graphene oxide ( Tan et al, 2020 ), molybdenum disulfide ( Li et al, 2020 ), metal organic framework ( Biswas et al, 2021 ), etc. MoS 2 , as a common two-dimensional material similar to graphene, is considered to be an excellent semiconductor material with good edge position, narrow band gap, large specific surface area, sensitivity to external environment, strong adsorption and other characteristics, and has been widely used in the preparation of immune sensors ( Lu et al, 2020 ; Gong et al, 2022 ; Roy et al, 2022 ).…”