Naltrexone plus benzodiazepine aids abstinence in opioid-dependent patients

Stella, L.; D'Ambra, Ciro; Mazzeo, Filomena; Capuano, Annalisa; Franco, Francesco Del; Avolio, Amalia; Ambrosino, Francesco

doi:10.1016/j.lfs.2005.05.036

Cited by 26 publications

(26 citation statements)

References 16 publications

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“…There has been an increase in the use of buprenorphine rather than methadone in community MMT clinics [17,18]; two questions related to buprenorhine were therefore added. Naltrexone is another substitute drug that is used increasingly to prevent relapse of opioid-dependent patients [19,20], and two questions on naltrexone were also included in the questionnaire. These seven items were scattered throughout the 52-item instrument, but were not part of any of the scales.…”

Section: Methodsmentioning

confidence: 99%

Attitudes and beliefs towards methadone maintenance treatment among Australian prison health staff

Gjersing

Butler

Caplehorn

et al. 2007

Drug and Alcohol Review

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This is the first survey to examine prison health staff attitudes to methadone treatment. Correctional health staff tend to be more abstinence-orientated, more likely to disapprove of drug use, and less knowledgeable about the risks and benefits of methadone than Australian community methadone staff. The findings have important implications for training health staff working in the prison environment with regard to client retention on methadone treatment.

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Section: Methodsmentioning

confidence: 99%

Attitudes and beliefs towards methadone maintenance treatment among Australian prison health staff

Gjersing

Butler

Caplehorn

et al. 2007

Drug and Alcohol Review

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“…Moreover, these substances are more and more used by athletes not only in competitive sports, but also in fitness and recreational sports. It is important to ask why athletes dope (Stella et al, 2005). One thing is certain the substances that give pleasant sensations or help the subject in his activity will bring him to repeat the consumption.…”

Section: Table 1 Wada 2018 Prohibited Listmentioning

confidence: 99%

“…Stimulants are used to increase the concentration, alertness and safety. They also increase the aggressiveness and the sense of competitiveness (Stella et al, 2005). To anabolic are recognized for the following effects: euphoria, sense of wellbeing, glee, increased motivation and self-esteem.…”

Section: Table 1 Wada 2018 Prohibited Listmentioning

confidence: 99%

Sport, Drugs and Health promotion: Pharmacological and Epidemiological aspects

2019

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Sport activity, must be directed to the promotion of individual and collective health. Thus, there is no doubt that drugs and pharmacological nutriment have been used by sportsmen and women to improve his physical performance. Doping is defined as "use of substances or adoption of medical practices not justified by pathological conditions, aimed at improving competitive performance". It occurs not only in professional sport, but also affects amateur athletes. The effects of the abuse of add-on substances or the intake of substances that alter the outcome of the competition are in the educational interest of the school and it is a problem concerning not only sports ethics, but also public health. Over time, doping has shown a great ability to discover and always use new substances and appropriated the new scientific discoveries. Unfortunately, new discoveries for the human health are been used in distorted way by the athletes. In fact, the athletes may be able to use gene therapy to re-engineer their bodies for better performances. Drugs dependence depends on several factors: the socio-environmental context of the subject and what effects have the substance in the body. The purpose of the study was to reviewed the use of performance-enhancing drugs in sport in relating to the protection of the healh of athletes. We focus our analysis on pharmacological and epidemiological issue.

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“…Therefore, pharmacologic interventions that specifically target the negative affectivity, which co-occurs with drug cue– and stress–induced craving, could be of benefit in improving naltrexone treatment outcomes for opioid dependence. 18,19 Stella and co-workers 19 evaluated whether naltrexone combined with the benzodiazepine prazepam was more effective than naltrexone alone in keeping patients opioid free. Relapse rates over 6 months in 56 opioid-dependent subjects were compared among 4 groups with an equal sample size.…”

Section: Combinations With Other Medicationsmentioning

confidence: 99%