Nail psoriasis masqueraded by secondary infection with <i><scp>R</scp>hodotorula mucilaginosa</i>

Martini, K.; Müller, Hannes M.; Huemer, Hartwig P.; Höpfl, Reinhard

doi:10.1111/myc.12091

Cited by 11 publications

(12 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…No additional studies were found by hand‐screening of the included articles’ references. Finally, 111 met the criteria . Additional information was kindly provided by the corresponding author of one study .…”

Section: Resultsmentioning

confidence: 99%

Rhodotorula species infections in humans: A systematic review

Ιωάννου

Vamvoukaki

Samonis

2018

Mycoses

View full text Add to dashboard Cite

| INTRODUC TI ONRhodotorula belongs to the phylum Basidiomycota and forms spherical-to-ellipsoidal budding yeast as well as rudimentary hyphae and small capsules. 1 It is widely distributed in the environment and is also found in the normal flora of the human gastrointestinal, respiratory and genital system as well as in the moist areas of the skin. 2 Even though it had been considered nonpathogenic, in the last decades there is growing evidence that it can be important human pathogen, especially in immunocompromised hosts, causing a variety of different infections, such as fungaemia, meningitis, peritoneal dialysis-associated peritonitis and keratitis. 3,4 The purpose of this study was to systemically review all published cases of Rhodotorula infections in the literature and describe the epidemiology, microbiology, treatment and outcomes of these infections in humans. SummaryBackground: Fungal infections by Rhodotorula species are increasingly reported in the literature and consist of bloodstream infections, especially in patients with central venous catheters (CVC), as well as central nervous system (CNS), ocular and other less frequent infections. Objectives: The aim of this systematic review was to record and evaluate all available evidence regarding infections by Rhodotorula species. Methods: Systematic review of PubMed (through 9 August 2017) for studies providing epidemiological, clinical, microbiological, as well as treatment data and outcomes of Rhodotorula species infections.Results: A total of 111 studies, containing data of 248 patients, were eventually included in the analysis. The most common Rhodotorula infections were those of bloodstream, CNS and ocular infections, as well as peritoneal dialysis-associated peritonitis.Epidemiology of each type of infection was different, with the bloodstream ones being more common in patients with malignancy and CVCs, while those of the CNS were more common in patients with AIDS. Mortality was variable being higher in CNS infections. Amphotericin B remains the most common agent used for treatment, irrespectively of the infection site. Conclusions: This systematic review thoroughly describes fungal infections byRhodotorula species and provides information on their epidemiology, clinical picture, microbiology, treatment and outcomes. K E Y W O R D S fungaemia, fungal infection, keratitis, meningitis, peritonitis, Rhodotorula | 91 IOANNOU et Al. with the following text-word: Rhodot*[tw]. Day of last search was 9 August 2017. | Study selectionStudies were included in analysis if they met the following criteria: (a) published in English; and (b) reporting data on patients' clinical characteristics, microbiology, treatment and outcomes. From the analysis were excluded studies with the following criteria: (a) secondary research papers (eg, reviews), editorials and papers not reporting results on primary research; (b) studies not in humans; (c) studies on colonisation but not infection by Rhodotorula; and (d) studies not in English. Two investigators (PI and RV) using Ab...

show abstract

Section: Resultsmentioning

confidence: 99%

Rhodotorula species infections in humans: A systematic review

Ιωάννου

Vamvoukaki

Samonis

2018

Mycoses

View full text Add to dashboard Cite

show abstract

“…Probably yes. The fungal nail infection could act as a type of Koebner phenomenon, leading to worsening or even triggering nail psoriasis . Ghosal et al .…”

Section: Does Onychomycosis Act As Koebner Phenomenon and Exacerbatesmentioning

confidence: 99%

“…The fungal nail infection could act as a type of Koebner phenomenon, leading to worsening or even triggering nail psoriasis. 29,33 Ghosal et al [34] found that nail psoriasis was more frequent in psoriatic patients with skin Koebner phenomenon than in patients On the other hand, it must be emphasised that a higher NAPSI score means a more distracted nail unit barrier and as a result, an easier penetration of the pathogenic microorganisms. Further studies addressing this question are warranted.…”

Section: Does Onychomycosis Act As Koebner Phenomenon and Exacerbatmentioning

confidence: 99%

Onychomycosis in patients with nail psoriasis: a point to point discussion

Rigopoulos

Papanagiotou

Daniel

et al. 2016

Mycoses

View full text Add to dashboard Cite

Onychomycosis is the most common nail disease and affects large parts of the population. Psoriasis is a frequently encountered skin disorder with nail involvement being found in up to 80% of the patients at some time of the course of the disease. It has been postulated that onychomycosis occurs more frequently in patients with nail psoriasis, but the results of studies in the literature are controversial. Moreover, onychomycosis could exacerbate psoriasis through Koebner phenomenon and the treatment of psoriasis could predispose to onychomycosis. Finally, the differential diagnosis could be a real challenge due to many same clinical signs, the high prevalence and the possible coexistence of the two diseases. This article attempts to enlighten all these different aspects of a very close relationship.

show abstract

“…Authors suggested that this yeast could be a primary agent of onychomycosis. Another case report showed that nails subject to psoriasis were secondarily infected by R. mucilaginous [17]. Both cases caused by R. mucilaginous appeared in fingernails or toenails of immunocompetent individuals.…”

Section: Discussionmentioning

confidence: 99%

Different toenail onychomycosis due to Rhodotorula mucilaginosa and Candida parapsilosis in an immunocompetent young adult

Mei

et al. 2019

Medical Mycology Case Reports

View full text Add to dashboard Cite

Candida parapsilosis ( C. parapsilosis ) and Rhodotorula mucilaginosa ( R. mucilaginosa ) have emerged as a potential pathogen in immunosuppressed hosts; they rarely induce onychomycosis in immunocompetent hosts without assistance from other pathogens. Here we present onychomycosis induced by two strains on different toenails in an immunocompetent young adult. The patient presented with onychomycosis on left and right first toenails due to R. mucilaginosa and C. parapsilosis , respectively. Based on the diagnosis, he had been orally treated with itraconazole 200 twice daily for one week every four weeks that repeated 7 times; however, the toenails did not respond satisfactorily to the treatment. After two months of drug cessation, we confirmed that the two toenails were infected with different fungi. R. mucilaginosa was isolated from the left first toenail, and C. parapsilosis was isolated from the right first toenail. Identifications were confirmed by morphological and cultural characteristics as well as by DNA molecular analysis. After determining in vitro drug susceptibility, the patient was successfully treated with a topical application of ketoconazole cream on the left toenail and oral itraconazole. It is the rare known case of different nails being infected by R. mucilaginosa and C. parapsilosis respectively.

show abstract

Nail psoriasis masqueraded by secondary infection with Rhodotorula mucilaginosa

Cited by 11 publications

References 8 publications

Rhodotorula species infections in humans: A systematic review

Rhodotorula species infections in humans: A systematic review

Onychomycosis in patients with nail psoriasis: a point to point discussion

Different toenail onychomycosis due to Rhodotorula mucilaginosa and Candida parapsilosis in an immunocompetent young adult

Contact Info

Product

Resources

About