Nafcillin Resistant Staphylococcus Aureus A Possible Community Origin

Hamoudi, Ayser C.; Palmér, Robert; King, Timothy L.

doi:10.1017/s0195941700058070

Cited by 25 publications

(6 citation statements)

References 16 publications

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“…Twenty-seven of the studies were retrospective [5,10,, and 6 different definitions of CA-MRSA were seen in 21 of these [5, 10, 17, 19-22, 24-32, 34, 37, 38, 40, 41]. Six retrospective studies did not report the definition used [18,23,33,35,36,39]. Five publications were prospective studies, and 3 different definitions of CA-MRSA were used in this group [12][13][14][15][16].…”

Section: Resultsmentioning

confidence: 99%

Community‐Acquired Methicillin‐ResistantStaphylococcus aureus:A Meta‐Analysis of Prevalence and Risk Factors

Salgado¹,

Farr²,

Calfee³

2003

CLIN INFECT DIS

719

500

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Reports suggest that carriage of methicillin-resistant Staphylococcus aureus (MRSA) among persons without health care-associated risks has increased. A meta-analysis of studies reporting the prevalence of community-acquired MRSA (CA-MRSA) among MRSA isolates from hospitalized patients or the prevalence of MRSA colonization among community members was conducted. The CA-MRSA prevalence among hospital MRSA was 30.2% in 27 retrospective studies and 37.3% in 5 prospective studies; 85% of all patients with CA-MRSA had > or =1 health care-associated risk. The pooled MRSA colonization rate among community members was 1.3% (95% confidence interval [CI], 1.04%-1.53%), but there was significant heterogeneity among study populations. Community members from whom samples were obtained in health care facilities were more likely to be carrying MRSA than were community members from whom samples were obtained outside of the health care setting (relative risk, 2.35; 95% CI, 1.56-3.53). Among studies that excluded persons with health care contacts, the MRSA prevalence was 0.2%. Moreover, most persons with CA-MRSA had > or =1 health care-associated risk, which suggests that the prevalence of MRSA among persons without risks remains low (< or =0.24%). Effective control of dissemination of MRSA throughout the community likely will require effective control of nosocomial MRSA transmission.

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Section: Resultsmentioning

confidence: 99%

Community‐Acquired Methicillin‐ResistantStaphylococcus aureus:A Meta‐Analysis of Prevalence and Risk Factors

Salgado¹,

Farr²,

Calfee³

2003

CLIN INFECT DIS

719

500

View full text Add to dashboard Cite

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“…Community onset MRSA infections have been recognized in children without established risk factors at least since the early 1980s, 16 and the incidence of these infections appears to be increasing. Perhaps more ominously all three Staphylococcus aureus isolates from that year were resistant to semisynthetic penicillins.…”

Section: Discussionmentioning

confidence: 99%

Untitled

Buckingham

KING

Miller

2003

Pediatr Infect Dis J

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The incidence of complicated parapneumonic effusions in children with community-acquired pneumonia increased from 1996 to 1999 and then declined concomitant with the introduction of the pneumococcal conjugate vaccine. Although cases caused by S. pneumoniae have decreased, community onset methicillin-resistant Staphylococcus aureus has emerged as a cause of pneumonia with complicated effusions in children.

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“…Scattered case reports describing patients with none of the known health care-associated risk factors for MRSA that had MRSA colonization or a clinical infection were published in the 1980s and the mid-1990s (29,64,205,339,359,530,711,748,801), including several outbreaks caused by different MRSA strain types in remote regions in Western Australia and then in the Northern Territory of Australia (670). Subsequently, beginning in 1993, case series of MRSA infection and colonization of patients lacking health care-associated risk factors were reported from six continents, in diverse states, nations, and regions (Table 3).…”

Section: Ca-mrsa: An Epidemic and Its Originsmentioning

confidence: 99%

Community-Associated Methicillin-ResistantStaphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic

2010

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SUMMARY Staphylococcus aureus is an important cause of skin and soft-tissue infections (SSTIs), endovascular infections, pneumonia, septic arthritis, endocarditis, osteomyelitis, foreign-body infections, and sepsis. Methicillin-resistant S. aureus (MRSA) isolates were once confined largely to hospitals, other health care environments, and patients frequenting these facilities. Since the mid-1990s, however, there has been an explosion in the number of MRSA infections reported in populations lacking risk factors for exposure to the health care system. This increase in the incidence of MRSA infection has been associated with the recognition of new MRSA clones known as community-associated MRSA (CA-MRSA). CA-MRSA strains differ from the older, health care-associated MRSA strains; they infect a different group of patients, they cause different clinical syndromes, they differ in antimicrobial susceptibility patterns, they spread rapidly among healthy people in the community, and they frequently cause infections in health care environments as well. This review details what is known about the epidemiology of CA-MRSA strains and the clinical spectrum of infectious syndromes associated with them that ranges from a commensal state to severe, overwhelming infection. It also addresses the therapy of these infections and strategies for their prevention.

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Nafcillin Resistant Staphylococcus Aureus A Possible Community Origin

Cited by 25 publications

References 16 publications

Community‐Acquired Methicillin‐ResistantStaphylococcus aureus:A Meta‐Analysis of Prevalence and Risk Factors

Community‐Acquired Methicillin‐ResistantStaphylococcus aureus:A Meta‐Analysis of Prevalence and Risk Factors

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Community-Associated Methicillin-ResistantStaphylococcus aureus: Epidemiology and Clinical Consequences of an Emerging Epidemic

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