NADPH-diaphorase-positive cells in the thalamic nuclei and internal capsule in humans

Morphology of NOS-immunoreactive Neurons in the Human Thalamic Reticular Nucleus and its Clinical Implications

“…The comparison of the large R1 reticular neurons with their identical types in the ventral anterior and ventral lateral nuclei of the human thalamus showed that the nature of branching in the former was the same [3]. Our previous studies on the presence and morphology of NADPH-diaphorase positive neurons in the human TRN [22], and also the study of Berezhnaya [4] on these neurons and the ones in the internal capsule, located lateral to the TRN, demonstrate without any doubt the presence of NADPH-diaphorase positive neurons in these structures of the human brain. Nitric oxide is a small, highly diffusible, and reactive molecule with a short lifespan that is generated by nitric oxide synthase (NOS) through enzymatic conversion of L-arginine to L-citrulline [1,9].…”