“…Antioxidant system genes involved in glutathione metabolism (CD44, GCLM, GSTP1, GLRX2, GLRX3, GPX1, GPX2, GPX3, GPX4, and SLC3A2), thioredoxin metabolism (PRDX1, PRDX2, PRDX6, TXN, TXNL1, and TXNRD1), quinone detoxification (NQO1), and iron storage (FTH1, FTL, and PCBP1) were also enriched in the INS lo UPR hi state and protect against ROS (Fig. 5) (34)(35)(36)(37).…”