NAD+ associated genes as potential biomarkers for predicting the prognosis of gastric cancer
XIANGDONG SUN,
HUIJUAN WEN,
FAZHAN LI
et al.
Abstract:Nicotinamide adenine dinucleotide (NAD+) plays an essential role in cellular metabolism, mitochondrial homeostasis, inflammation, and senescence. However, the role of NAD+-regulated genes, including coding and long non-coding genes in cancer development is poorly understood. We constructed a prediction model based on the expression level of NAD+ metabolism-related genes (NMRGs). Furthermore, we validated the expression of NMRGs in gastric cancer (GC) tissues and cell lines; additionally, β-nicotinamide mononuc… Show more
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