Nachweis einer Resistenzentwicklung bei der Leuk�mie L 1210 mit dem in vitro-Kurzzeittest

Abstract

By treatment of the mouse leukemia L 1210 with cytosinarabinoside (120 mg/kg per week) a tumour cell line was developed which was resistant to this cytostatic agent. It is possible, using the short-term test, to follow the development of resistance to cytosinarabinoside.