Nabilone for the Treatment of Post-Traumatic Stress Disorder: A 2021 Update

Abstract


 Two systematic reviews that met the inclusion criteria of this report were identified. Within these reviews, the clinical effectiveness of nabilone for the treatment of adult patients with post-traumatic stress disorder (PTSD) was evaluated in 1 relevant primary study. This single-arm, open-label study found that most patients with PTSD experienced total cessation or reduction of nightmares following treatment with nabilone. This study lacked a control group, limiting the certainty of these findings.
 No evidence-based guidelines regarding the use of nabilone for the treatment of adult patients with PTSD were identified.