Abstract:The goal of this study was to develop taste-masked orally disintegrating tablets of the bitter-tasting levocetirizine dihydrochloride (LCDH) to improve the accessibility and adherence of pediatric, elderly, non-cooperative and paraplegic patients. Methods: In the present study, orally disintegrating Levocetirizine dihydrochloride tablets were formulated by direct compression. Taste masking was achieved using a pH-independent polymeric dispersion of Surelease E-7-19040 in combination with Opadry YS-1-19025-A in… Show more
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