N-Nitrosation Based Fluorescence Turn-On Nitric Oxide Probe: Kinetic and Cell Imaging Studies
Ananya Dutta,
Debjani Maiti,
Atul Katarkar
et al.
Abstract:Nitric
oxide (NO) is a ubiquitous messenger molecule playing a
key role in various physiological and pathological processes. However,
producing a selective turn-on fluorescence response to NO is a challenging
task due to (a) the very short half-life of NO (typically in the range
of 0.1–10 s) in the biological milieu and (b) false positive
responses to reactive carbonyl species (RCS) (e.g., dehydroascorbic
acid and methylglyoxal etc.) and some other reactive oxygen/nitrogen
species (ROS/RNS), especially with o-… Show more
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