The free metaplectic transformation is an N-dimensional linear canonical transformation. This transformation operator is useful, especially for signal processing applications. In this paper, in order to characterize simultaneously local analysis of a function (or signal) and its free metaplectic transformation, we extend some different uncertainty principles (UP) from quantum mechanics including Classical Heisenberg’s uncertainty principle, Nazarov’s UP, Donoho and Stark’s UP, Hardy’s UP, Beurling’s UP, Logarithmic UP, and Entropic UP, which have already been well studied in the Fourier transform domain.