2017
DOI: 10.24193/subbchem.2017.2.29
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N'-Benzylidene-N-(Thiazolyl)Acetohydrazide Derivatives: Synthesis and Antimicrobial Activity Evaluation

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“…Our previous results in the synthesis and characterization of biologically active novel thiazole derivatives described several 2-hydrazinyl-thiazole derivatives which displayed antibacterial, analgesic, or anti-inflammatory activities [2][3][4][5]. Various heterocyclic systems containing thiazole units joint or fused to other aromatic moieties were synthesized and several aspects of their biological activities were described; thus, some benzothiazolophenothiazine derivatives exhibited antimicrobial activity [6][7][8][9], while bis(thiazolyl)-, phenothiazinyl-and indolyl-thiazolylhydrazine derivatives were screened for their anticancer potential [10][11][12][13][14][15][16][17][18][19] in search for new antitumour agents producing less hypersensitivity side reactions (which might occur due to platinum complexes which are currently employed in the cancer therapy. [20]).…”
mentioning
confidence: 99%
“…Our previous results in the synthesis and characterization of biologically active novel thiazole derivatives described several 2-hydrazinyl-thiazole derivatives which displayed antibacterial, analgesic, or anti-inflammatory activities [2][3][4][5]. Various heterocyclic systems containing thiazole units joint or fused to other aromatic moieties were synthesized and several aspects of their biological activities were described; thus, some benzothiazolophenothiazine derivatives exhibited antimicrobial activity [6][7][8][9], while bis(thiazolyl)-, phenothiazinyl-and indolyl-thiazolylhydrazine derivatives were screened for their anticancer potential [10][11][12][13][14][15][16][17][18][19] in search for new antitumour agents producing less hypersensitivity side reactions (which might occur due to platinum complexes which are currently employed in the cancer therapy. [20]).…”
mentioning
confidence: 99%