“…In contrast, incorporation of smaller aryloxo substituents affords compounds such as 130 that display selective MAO-B inhibitory properties comparable to 126 (255). In some recent studies, MAO-B potency and selectivity of 126 have been dramatically improved by replacement of the amidyl moiety with the corresponding ester or carbamate bioisosteres as shown with 131 and 132, respectively (256,257). 10.12.…”