2009 Help me understand this report
N-Alkylation-Intramolecular Michael Addition: New Reaction Manifold for High Throughput Annulation of Amines
Abstract: Parallel synthesis of a-substituted pyrrolidines, piperidines, morpholines, piperazines and diazaspirocycles was achieved in a single reaction step via the annulation of primary amines with halo-2-alkenyl esters, amides, nitriles and phenylsulfones.
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