N-Acetyl peak in proton MR spectroscopy of metastatic mucinous adenocarcinoma of brain

Aziz, Zarina; Jethwani, Dilip; Ram, G Ananta; Kumar, Gaurav; Saini, Jitender

doi:10.1007/s00062-012-0137-2

Cited by 2 publications

(2 citation statements)

References 21 publications

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“…However, PAs are often positive on PAS staining for polysaccharides. Several groups have reported NA‐signal in mucin‐containing lesions , with Andre et al describing N‐acetylated sugars such as N‐acetylgalactosamine or N‐acetylglucosamine as likely candidates. In our study, we observed significantly increased signal intensity in the 3.3 to 4.0 ppm region of PA, which would support the presence of these or similar molecules with NA groups attached to sugar rings.…”

Section: Discussionmentioning

confidence: 99%

“…Indeed, there have been several studies in which prominent signal similar to that of NAA, but not attributed to NAA, has been reported. These include magnetic resonance spectroscopy (MRS) studies of metastatic mucinous adenocarcinomas of the brain ; colloid‐like brain cysts ; sinus mucoceles ; and, outside the brain in ovarian mucinous cystadenomas . All these lesions do have in common mucinous content.…”

Section: Introductionmentioning

confidence: 99%

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MRS of pilocytic astrocytoma: The peak at 2 ppm may not be NAA

2016

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

MRS of pilocytic astrocytoma: The peak at 2 ppm may not be NAA

2016

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Magnetic Resonance Spectroscopy Findings of Intracranial Chondroma and Chondrosarcoma with a Non-skull Base Origin: A Report of Two Cases

Amanpour-Gharaei,

Haghshenas Bilehsavar,

Pour-Rashidi

et al. 2023

Iran J Radiol

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Introduction: Intracranial chondroma and chondrosarcoma are very rare tumors that mainly originate from the base of the skull. Advanced neuroimaging studies, including magnetic resonance spectroscopy (MRS), play a pivotal role in both tumor diagnosis and presurgical planning. Case Presentation: We present two cases of intracranial cartilaginous tumors, including a chondroma and a chondrosarcoma, both of which presented with severe headaches. Due to inconclusive conventional MRI and MRS results, they were both primarily diagnosed as intra-axial brain tumors. However, pathological reports later confirmed the diagnosis of a chondroma and a chondrosarcoma. Conclusion: Based on the present findings, the use of advanced neuroimaging techniques, such as MRS, may improve diagnostic accuracy. We believe that MRS can play a significant role in the surgical planning of similar cases. Also, reporting rare cases worldwide can contribute to the improvement of radiographic diagnosis.

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N-Acetyl peak in proton MR spectroscopy of metastatic mucinous adenocarcinoma of brain

Cited by 2 publications

References 21 publications

MRS of pilocytic astrocytoma: The peak at 2 ppm may not be NAA

MRS of pilocytic astrocytoma: The peak at 2 ppm may not be NAA

Magnetic Resonance Spectroscopy Findings of Intracranial Chondroma and Chondrosarcoma with a Non-skull Base Origin: A Report of Two Cases

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