N-3 HUFAs affect fat deposition, susceptibility to oxidative stress, and apoptosis in Atlantic salmon visceral adipose tissue

Todorčević, Marijana; Kjær, Marte Avranden; Djaković, Nataša; Vegusdal, Anne; Torstensen, Bente E.; Ruyter, Bente

doi:10.1016/j.cbpb.2008.10.009

Cited by 87 publications

(72 citation statements)

References 46 publications

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“…These results indicated that the number of mitochondria may increase during adipocytes differentiation, which is consistent with numerous in vitro studies in mammals [19][20][21][22]. In contrast, studies in Atlantic salmon observed a reduced number of mitochondria during adipocyte differentiation [43]. It was pointed out that fatty acid oxidation which occur in mitochondria would reduce intracellular triglyceride accumulation [44].…”

Section: Discussionsupporting

confidence: 57%

Morphology, mitochondrial development and adipogenic-related genes expression during adipocytes differentiation in grass carp (Ctenopharyngodon idellus)

et al. 2015

Science Bulletin

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Section: Discussionsupporting

confidence: 57%

Morphology, mitochondrial development and adipogenic-related genes expression during adipocytes differentiation in grass carp (Ctenopharyngodon idellus)

et al. 2015

Science Bulletin

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“…In the superclass osteichthyes, WAT has been described in the common carp ( Cyprinus carpio ; Gesta et al, 2007) and Atlantic salmon ( Salmo salar ; Todorcevic et al, 2009), but it has not been well characterized in zebrafish ( Danio rerio ). Although adipose tissue has been described in adult zebrafish and physiological and morphological similarities to mammals have been demonstrated (Song and Cone, 2007; Flynn et al, 2009), little is known about WAT development in vivo in fish or in mammals.…”

Section: Introductionmentioning

confidence: 99%

White adipose tissue development in zebrafish is regulated by both developmental time and fish size

Imrie

Sadler

2010

Developmental Dynamics

114

127

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Adipocytes are heterogeneous. Whether their differences are attributed to anatomical location or to different developmental origins is unknown. We investigated whether development of different white adipose tissue (WAT) depots in zebrafish occurs simultaneously or whether adipogenesis is influenced by the metabolic demands of growing fish. Like mammals, zebrafish adipocyte morphology is distinctive and adipocytes express cell-specific markers. All adults contain WAT in pancreatic, subcutaneous, visceral, esophageal, mandibular, cranial, and tail-fin depots. Unlike most zebrafish organs that form during embryogenesis, WAT was not found in embryos or young larvae. Instead, WAT was first identified in the pancreas on 12 days postfertilization (dpf), and then in visceral, subcutaneous, and cranial stores in older fish. All 30 dpf fish exceeding 10.6 mm standard length contained the adult repertoire of WAT depots. Pancreatic, esophageal, and subcutaneous WAT appearance correlated with size, not age, as found for other features appearing during postembryonic zebrafish development. Developmental Dynamics 239:3013-3023,

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“…The ability to store fats is conserved from yeasts to humans, although the type of fat stored and the sites of storage differ among species (23). Insects store fat exclusively in a fat body (69,78), mammals and birds store fat in abdominal and subcutaneous adipose tissue, and fish store fat in their liver, muscle and, in some species, adipose tissue (26,31,64,65,72). These stored fats provide an important source of energy (77), not only during periods of starvation or fasting when dietary lipids are completely lacking, but also during certain stages in an animal's life cycle when energy requirements may chronically exceed the energy available in the diet (e.g., during migration or during provisioning of energy-rich gametes).…”

mentioning

confidence: 99%

Triacylglyceride physiology in the short-finned eel,Anguilla australis—changes throughout early oogenesis

Damsteegt

Falahatimarvast

McCormick

et al. 2015

American Journal of Physiology-Regulatory, Integrative and Comp

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During certain stages in an animal's life cycle, energy requirements may exceed energy intake from the diet. The spawning migration of temperate eels is a textbook example of negative energy balance, forcing these fish to rely on stored fats (triacylglycerides) to provide their muscles with energy for swimming and their growing oocytes with the nutrients needed to develop and support healthy offspring. We predicted broad implications of this great need for endogenous triacylglycerides in terms of their packaging, transport, and ovarian uptake. To test this, serum lipid concentrations and transcript abundances of intestinal and hepatic triacylglyceride packagers and ovarian triacylglyceride modifiers and receivers were investigated throughout previtellogenesis (feeding phase) and into early vitellogenesis (fasting phase) in short-finned eels. A switch from exogenous to endogenous triacylglyceride packaging was seen as the liver upregulated transcript levels of apolipoprotein B and microsomal triacylglyceride transport protein and downregulated those of apolipoprotein E and lipoprotein lipase. In the intestine, the reverse response was observed. Furthermore, ovarian transcript abundances of triacylglyceride modifiers and receivers increased (apolipoprotein E, lipoprotein lipase, and vitellogenin receptor), indicative of increased triacylglyceride uptake during previtellogenesis. We propose that increased hepatic apolipoprotein B production is a conserved vertebrate response to prolonged periods of negative energy balance.

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N-3 HUFAs affect fat deposition, susceptibility to oxidative stress, and apoptosis in Atlantic salmon visceral adipose tissue

Cited by 87 publications

References 46 publications

Morphology, mitochondrial development and adipogenic-related genes expression during adipocytes differentiation in grass carp (Ctenopharyngodon idellus)

Morphology, mitochondrial development and adipogenic-related genes expression during adipocytes differentiation in grass carp (Ctenopharyngodon idellus)

White adipose tissue development in zebrafish is regulated by both developmental time and fish size

Triacylglyceride physiology in the short-finned eel,Anguilla australis—changes throughout early oogenesis

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