Myxoid pleomorphic liposarcoma of the falciform ligament: a rare case report

AlObaid, Bashayer; Alzahrani, Nayef; Shokor, Nada; Alshammari, Kanan

doi:10.1093/jscr/rjac531

Cited by 2 publications

(1 citation statement)

References 4 publications

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“…It mainly occurs in children and infants, and is extremely rare in adults [1][2]. It is characterized by a combination of pleomorphic and myxoid liposarcoma histology [3]. Because the disease incidence and location of rare disease, most of the literature at home and abroad is given priority to with a single case of case reports, some of these cases have occurred in the lung, pleural and mediastinal lung [4][5][6][7][8][9].…”

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confidence: 99%

Primary myxoid pleomorphic liposarcoma in the anterior mediastinum a case report

Wen,

Tang,

et al. 2023

Preprint

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Liposarcoma is a relatively rare malignant tumour of the adipose tissue, can happen in any place, including myxoid pleomorphic liposarcoma (MPL) is a special subtype of liposarcoma, common in children and infants and young children, very low incidence of mediastinum. The literature on mediastinal myxoid pleomorphic liposarcoma published at home and abroad are only case reports, so the clinical symptoms and imaging features are lack of specificity, and the diagnosis is challenging. Finally, postoperative pathology is still needed to confirm the diagnosis. In order to further improve the understanding of myxoid pleomorphic liposarcoma, we report a case of primary mediastinal myxoid pleomorphic liposarcoma with chest pain as the main symptom. The patient was discharged after complete surgical resection. This paper aimed to the disease of clinical, radiological features, pathology, diagnosis and treatment were analyzed and summarized.

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Section: Introductionmentioning

confidence: 99%

Primary myxoid pleomorphic liposarcoma in the anterior mediastinum a case report

Wen,

Tang,

et al. 2023

Preprint

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Rare myxoid pleomorphic liposarcoma: a case report and literature review

Shen,

Zhao,

et al. 2023

J Clin Pathol

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We report a case of a middle-aged woman with a rapidly growing abdominal mass that was diagnosed as myxoid pleomorphic liposarcoma, a recently recognised, rare and aggressive subtype of liposarcoma. The tumour exhibits a combination of histological features from both myxoid liposarcoma and pleomorphic liposarcoma. Genetic analysis revealed mutations in TP53 and RB1, along with widespread loss of heterozygosity. However, no DDIT3 gene translocation or MDM2/CDK4 gene amplification was detected. These genetic characteristics can be used to distinguish this type of liposarcoma from others. Two unusual gene fusion/rearrangements,CREB5::TERTfusion andETV1::LFNGrearrangement, were identified. The patient underwent complete removal of the tumour without the use of radiotherapy or chemotherapy. No recurrence was observed during the follow-up period of 18 months.

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Myxoid pleomorphic liposarcoma of the falciform ligament: a rare case report

Cited by 2 publications

References 4 publications

Primary myxoid pleomorphic liposarcoma in the anterior mediastinum a case report

Primary myxoid pleomorphic liposarcoma in the anterior mediastinum a case report

Rare myxoid pleomorphic liposarcoma: a case report and literature review

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