Myxoid neurofibroma of the male breast: fine needle aspiration cytodiagnosis

Hock, Y L; Mohamid, Waria

doi:10.1111/j.1365-2303.1995.tb00007.x

Cited by 8 publications

(7 citation statements)

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“…Myxoid myofibroblastoma is a myofibroblastic tumor which typically expresses desmin and variable α-smooth muscle actin, CD34, bcl-2, CD99, CD10, and estrogen/progesterone/ androgen receptors [21,22]. Lastly, myxoid neurofibroma is a tumor that expresses S100 protein and CD34 [19].…”

Section: Discussionmentioning

confidence: 98%

“…Practically, however, the lesions reported in the breast with diffuse myxoid stromal changes are: superficial angiomyxoma [9], nodular mucinosis (first reported as nerve sheath myxoma) [16,17], nodular fasciitis (myxoid variant) [18], neurofibroma (myxoid variant) [19,20], myofibrolastoma (myxoid variant) [21,22], myxofibrosarcoma [23], myxoid liposarcoma [24], and mucocele-like tumors [15]. A list of these lesions, including their main clinico-pathological features, is provided in Table 1.…”

Section: Discussionmentioning

confidence: 99%

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Clinico-pathological features of breast myxoma: report of a case with histogenetic considerations

2010

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We herein report the clinical, radiological, and pathological findings of a rare case of myxoma occurring in the breast parenchyma of a 75-year-old female. The tumor was incidentally detected at a mammographic screening and, ultrasonographically, presented as an ovoid mass. Histologically, an encapsulated hypocellular, myxoid tumor with low vascularization was evident. Neoplastic cells were round- to spindle/stellate-shaped and stained with vimentin and focally with calponin. We emphasize that morphology remains preeminent in the diagnosis of a breast myxoma, while immunohistochemistry may assist in ruling out other tumor entities. Differential diagnosis with all benign and malignant myxoid lesions, primarily occurring in the breast, is provided. The histogenesis of breast myxoma is unknown. The lack of expression of desmin, alpha-smooth muscle actin, CD34, CD99, CD10, bcl-2 protein, and estrogen/progesterone/androgen receptors, all markers characteristically expressed by "the benign spindle cell tumors of the mammary stroma," would suggest that breast myxoma does not fall into this tumor category and that its putative precursor mesenchymal cell resides in the interlobular stroma.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Clinico-pathological features of breast myxoma: report of a case with histogenetic considerations

2010

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“…Most neurofibromas occur as solitary lesions in the dermis or subcutis, are distributed evenly over the body surface, and occur very rarely in breast tissue (3, 4). Only a few cases of breast neurofibromas have been reported, both in men and women—excluding neurofibromas in the presence of neurofibromatosis (von Recklinghausen’s disease), which is considered a separate disease process (1, 2, 7, 8, 9). …”

Section: Discussionmentioning

confidence: 99%

Solitary neurofibroma of the breast

Thompson¹,

Kaplan²,

Poppiti³

et al. 2012

Radiology Case Reports

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“…Solitary neurofibromas of the breast are rare, even in women where only four cases have been reported [2,5,6]. In the male breast, there has been only one previous case [1]. This excludes the occurrence of neurofibromas in the presence of neurofibromatosis (von Recklinghausen's disease) which is regarded as a separate disease process.…”

Section: Discussionmentioning

confidence: 99%

“…Neurofibroma of the male breast is extremely rare with only one previous case having been reported [1]. …”

Section: Introductionmentioning

confidence: 99%